This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human PPARA, His-tagged
catalog :
PPARA-2740H
product information
Cat :
PPARA-2740H
Product Name :
Recombinant Human PPARA, His-tagged
Brand :
Creative Biomart
gene symbal :
PPARA
gene name :
peroxisome proliferator-activated receptor alpha
Synonyms :
PPARA; peroxisome proliferator-activated receptor alpha; peroxisome proliferative activated receptor, alpha , PPAR; hPPAR; NR1C1; MGC2237; MGC2452; Nuclear receptor subfamily 1 group C member 1; OTTHUMP00000197740; OTTHUMP00000197741; Peroxisome proliferator activated receptor alpha; PPAR; PPAR-alpha; PPARA_HUMAN; PPARalpha; peroxisome proliferative activated receptor, alpha; peroxisome proliferator-activated nuclear receptor alpha var
Product Overview :
Recombinant Human PPARgamma (PPARg, nuclear receptor) cloned from human cDNA, is expressed inE. coli. The nuclear receptor consists of the ligand binding domain of human PPARg. The protein has a N-terminal His-tag and a thrombin cleavage site (the protein must be cleaved to co-crystallization trials with the ligands).
Description :
Recombinant Human PPARgamma (PPARg, nuclear receptor) cloned from human cDNA, is expressed inE. coli. The nuclear receptor consists of the ligand binding domain of human PPARg. The protein has a N-terminal His-tag and a thrombin cleavage site (the protein must be cleaved to co-crystallization trials with the ligands).There is evidence that a group of closely related nuclear receptors, called Peroxisome Proliferator-activated Receptors (PPARs), may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. The PPARs were first cloned as the nuclear receptors that mediate the effects of synthetic compounds called peroxisome proliferators on gene transcription. It soon became clear that eicosanoids and fatty acids can also regulate gene transcription through PPARs. They bind a specific element in the promoter region of target genes only as a heterodimer with the receptor for 9-cis retinoic acid, RXR (retinoid X receptor). Binding of the ligand of either receptor can activate the complex, but binding of both ligands simultaneously is more potent. Three PPAR isotypes have been identified: , (also called NUC1) and .
Source :
E coli
Purity :
98% by SDS-PAGE. The enzyme was observed as a single band migrating at a molecular weight of 32 kDa.
Storage :
-80 C. The enzyme is stable at 80 C 6 months. It is recommended that thawing and dilution of the enzyme be done within a short time before the start of the assay. After initial defrost, aliquot
UniProt ID :
Q07869
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
questions and comments