This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Phospholipase A2, Group V, His-tagged
catalog :
PLA2G5-71H
product information
Cat :
PLA2G5-71H
Product Name :
Recombinant Human Phospholipase A2, Group V, His-tagged
Brand :
Creative Biomart
gene symbal :
PLA2G5
gene name :
phospholipase A2, group V
Synonyms :
PLA2G5; phospholipase A2, group V; calcium-dependent phospholipase A2; Ca2+ dependent phospholipase A2; Calcium dependent phospholipase A2; DKFZp686C2294; Group V phospholipase A2; GV PLA2; gVPLA2; hVPLA(2); MGC46205; OTTHUMP00000044655; PA2G5_HUMAN; Phosphatidylcholine 2 acylhydrolase; Phosphatidylcholine 2-acylhydrolase 5; Phospholipase A2 group V; PLA2 10; PLA2 G5; PLA2-10; sPLA2 Type V; OTTHUMP00000002785; Ca2+-dependent phospholipase A2; GV-PLA2
Product Overview :
Recombinant Human Secreted Phospholipase A2-V expressed in E.coli was produced with N-terminal His-Tag. sPLA2-V His-Tagged Fusion protein is 15.5 kDa containing 118 amino acid residues of the human secreted phospholipase A2-V and 16 additional amino acid residues – His-Tag.
Description :
Recombinant Human Secreted Phospholipase A2-V expressed in E.coli was produced with N-terminal His-Tag. sPLA2-V His-Tagged Fusion protein is 15.5 kDa containing 118 amino acid residues of the human secreted phospholipase A2-V and 16 additional amino acid residues – His-Tag.Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipids, which represent another class of lipid mediators. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of low molecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense. This enzyme has been proposed to hydrolyze phosphatidylcholine (PC) in lipoproteins to liberate lyso-PC and free fatty acids in the arterial wall, thereby facilitating the accumulation of bioactive lipids and modified lipoproteins in atherosclerotic foci. In mice, sPLA2 expression significantly influences HDL particle size and composition and demonstrate that an induction of sPLA2 is required for the decrease in plasma HDL cholesterol in response to inflammatory stimuli.
Source :
Escherichia Coli
Purity :
Greater than 95% as determined by SDS PAGE.
Storage :
Store lyophilized protein at -20 C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 C for a limited period of time; it does not show any change after two weeks at 4 C. The lyophilized protein remains stable until the expiry date when stored at -20 C.
UniProt ID :
P39877
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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