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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human NTRK2, Fc Chimera
catalog :
NTRK2-109H
product information
Cat :
NTRK2-109H
Product Name :
Recombinant Human NTRK2, Fc Chimera
Brand :
Creative Biomart
gene symbal :
NTRK2
gene name :
neurotrophic tyrosine kinase, receptor, type 2
Synonyms :
NTRK2; neurotrophic tyrosine kinase, receptor, type 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine receptor kinase type 2;
Product Overview :
Recombinant Humantyrosine kinase receptor B was fused to the Fc region of human IgG1 (aa 93-330). The chimeric protein was expressed in modifiedhuman 293 cells.
Description :
Recombinant Humantyrosine kinase receptor B was fused to the Fc region of human IgG1 (aa 93-330). The chimeric protein was expressed in modifiedhuman 293 cells.The tropomyosin-related kinase (Trk) family consists of TrkA, TrkB and TrkC. TrkB is a high affinity receptor for BDNF and NT-4/5, and also binds NT-3 with lower affinity. TrkB is widely expressed, primarily in nervous tissue. The biological effects of TrkB activation are crucial in neuronal differentiation during embryonic development, specifically in the formation of the sympathetic nervous system. Additionally, the TrkB/BDNF complex facilitates the survival of post-mitotic neurons, axon growth and guidance as well as synaptic plasticity. TrkB also contributes to learning and spatial memory formation and the attenuation of injury-induced neuronal cell death. In addition to regulating CNS physiology TrkB and BDNF are involved in the formation of follicular growth and oocyte survival in the mammalian ovary.TrkB is a heavily glycosylated type I transmembrane protein of 791 amino acids, and the TrkB-Fc Chimera contains 13 potential N-linked glycosylation sites.
Source :
human 293 cells
Purity :
95%, as determined by SDS-PAGE and visualized by silver stain.
Storage :
Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C.
UniProt ID :
Q16620
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.