This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Noggin
catalog :
NOG-454H
product information
Cat :
NOG-454H
Product Name :
Recombinant Human Noggin
Brand :
Creative Biomart
gene symbal :
NOG
gene name :
noggin
Synonyms :
NOG; noggin
Product Overview :
Recombinat human Noggin was expressed in modifiedhuman 293 cells.
Description :
Recombinat human Noggin was expressed in modifiedhuman 293 cells.Noggin is a secreted glycoprotein predominantly expressed by the dorsal mesoderm during embryogenesis. Noggin has been shown to bind with high affinity to bone morphogenetic protein-4 (BMP-4) and with lower affinity to BMP-2 and BMP-7. Noggin specifically inhibits the action of BMP's by preventing interaction with their receptors. It has been shown that noggin maintains hES in an undifferentiated state in culture. Additionally, noggin in combination with FGF2 can maintain undifferentiated hES growth for substantial culture periods while retaining hES karyotype and pluripotency. The role of noggin in the maintenance of undifferentiated hES suggests it is potentially a valuable component of animal free hES cultures allowing hES to be applicable for therapeutic applications. Human noggin is a 205 amino acid glycoprotein and is secreted as a covalently linked homodimer of approximately 30 kDa with a similar structure to BMP-7.
Source :
human 293 cells
Purity :
95% as determined by SDS-PAGE and visualized by silver stain.
Storage :
Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C.
UniProt ID :
Q13253
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.