This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human NGFR, 222aa, Fc Chimera
catalog :
NGFR-453H
product information
Cat :
NGFR-453H
Product Name :
Recombinant Human NGFR, 222aa, Fc Chimera
Brand :
Creative Biomart
gene symbal :
NGFR
gene name :
nerve growth factor receptor
Synonyms :
NGFR; nerve growth factor receptor; p75; LNGFR; p75NTR; RNNGFRR; Tnfrsf16; tumor necrosis factor receptor superfamily member 16; p75 ICD; gp80-LNGFR; NGF receptor; nerve growth factor receptor, fast; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16);
Product Overview :
Recombinat human Nerve growth factor receptor was fused to the Fc region of human IgG1 (aa 93-330). It was expressed in modifiedhuman 293 cells.
Description :
Recombinat human Nerve growth factor receptor was fused to the Fc region of human IgG1 (aa 93-330). It was expressed in modifiedhuman 293 cells.Nerve growth factor receptor (NGFR), also known as p75NTR or CD271 antigen, is a low affinity NGF receptor primarily responsible for modulating the affinity and activity of tyrosine kinases that promote neuronal survival. Ligand binding by neurotrophins, including beta NGF, brain derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and neurotrophin-5 (NT4/5), to the NGF R can promote either survival or apoptosis of neurons. NGF receptors such as TrkA, B and C, can associate with NGF R to stimulate higher affinity ligand binding, although on its own NGF R binds to all neutrophins within equal affinity. Neurotrophin-NGFR signaling mediates conditions such as pain, depression, obesity, nerve regeneration disorders, learning and memory. Additionally, NGF R is thought to play a role in neuronal death that occurs in disorders of the CNS such as Alzheimer's disease.
Source :
human 293 cells
Purity :
95%, as determined by SDS-PAGE and visualized by silver stain.
Storage :
Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C.
UniProt ID :
P08138
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.