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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human MMP9, Catalytic Domain, T7-tagged
catalog :
MMP9-774H
product information
Cat :
MMP9-774H
Product Name :
Recombinant Human MMP9, Catalytic Domain, T7-tagged
Brand :
Creative Biomart
gene symbal :
MMP9
gene name :
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Synonyms :
MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); GELB; CLG4B; MMP-9; MANDP2; matrix metalloproteinase-9; 92 kDa gelatinase; type V collagenase; macrophage gelatinase; 92 kDa type IV collagenase; matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase);
Product Overview :
Recombinant human Metalloproteinase-9 (MMP-9, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, GELB) catalytic domain with fibronectins domains cloned from human cDNA, was expressed inE. coli. The recombinant enzyme consists of the catalytic domain of human MMP-9 (residues 112-445) with a N-term T7 tag. MW= 37.7kDa.
Description :
Recombinant human Metalloproteinase-9 (MMP-9, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, GELB) catalytic domain with fibronectins domains cloned from human cDNA, was expressed inE. coli. The recombinant enzyme consists of the catalytic domain of human MMP-9 (residues 112-445) with a N-term T7 tag. MW= 37.7kDa.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Source :
E coli
Purity :
95% by SDS-PAGE. In an SDS-PAGE gel, the enzyme runs as a single band migrating between 35 and 45 kDa.
Storage :
-80℃. It is recommended that thawing and dilution of the enzyme be done in ice and within as short a time as possible before start of the assay. After initial defrost, aliquot product into individual tubes and refreeze at -80℃. Avoid repeated freeze/defrost cycles.
UniProt ID :
P14780
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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