This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human MYC Associated Factor X, Flag-tagged
catalog :
MAX-2506H
product information
Cat :
MAX-2506H
Product Name :
Recombinant Human MYC Associated Factor X, Flag-tagged
Brand :
Creative Biomart
gene symbal :
MAX
gene name :
MYC associated factor X
Synonyms :
MAX; MYC associated factor X; bHLHd4; protein max; class D basic helix-loop-helix protein 4;
Product Overview :
Recombinant human Flag-tagged MAX was expressed in anE. colisystem and purified by affinity and FPLC chromatography. 18 kDa.
Description :
Recombinant human Flag-tagged MAX was expressed in anE. colisystem and purified by affinity and FPLC chromatography. 18 kDa.The MAX gene encodes a protein that interacts specifically with the Myc protein to form a heterodimer with high affinity for the specific cognate DNA-binding site of Myc. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include MAD, MXI1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Substantial evidence has been accumulated over the years that support the model that Myc/MAX/MAD proteins affect different aspects of cell behavior, including proliferation, differentiation, and apoptosis, by modulating distinct target genes. The unbalanced expression of these genes, e.g. in response to deregulated Myc expression, is most likely an important aspect of Myc`s ability to stimulate tumor formation. It is reported that in vivo transactivation assays suggest that Myc-MAX and MAD-MAX complexes have opposing functions in transcription and that MAX plays a central role in this network of transcription factors. High levels of MAX and stress-induced NF- κB activation may result in elevated expression of Fas ligand in human lung cancer cells and possibly contribute to Fas ligand- associated immune escape mechanisms.
Source :
E coli
UniProt ID :
P61244
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.