This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human HP, His-tagged
catalog :
HP-135H
product information
Cat :
HP-135H
Product Name :
Recombinant Human HP, His-tagged
Brand :
Creative Biomart
gene symbal :
HP
gene name :
HP haptoglobin [ Homo sapiens ]
Synonyms :
HP; haptoglobin;
Product Overview :
Recombinant fragment, corresponding to amino acids 145-405 of Human Haptoglobin.A single, non-glycosylated, polypeptide chain with a N terminal His tag and having a total MW of 33 kDa.
Description :
This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohns disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinsons disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
Source :
E. coli
Form :
Lyophilised:Reconstitute in sterile 18MOhm/cm water at not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Purity :
>90% by SDS-PAGE
Storage :
Shipped at 4 C. Upon delivery aliquot and store at -20 C or -80 C. Avoid repeated freeze / thaw cycles.
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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