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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human HGF
catalog :
HGF-8535H
product information
Cat :
HGF-8535H
Product Name :
Recombinant Human HGF
Brand :
Creative Biomart
gene symbal :
HGF
gene name :
hepatocyte growth factor (hepapoietin A; scatter factor)
Synonyms :
SF; HGFB; HPTA; F-TCF; DFNB39;Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor; Hepatocyte growth factor beta chain; Hepatocyte growth factor precursor; Hepatopoeitin-A; Hepatopoietin A; Hgf; Lung fibroblast derived mitogen; OTTHUMP00000161349; OTTHUMP00000206710; OTTHUMP00000206711; OTTHUMP00000206712; OTTHUMP00000206713; OTTHUMP00000206730; Scatter factor; Rilotumumab; 872514-65-3; Flanvotumab; 1188277-05-5
Product Overview :
A DNA sequence encoding the human HGF ( NP_000592.3 ) precursor ( Met 1 - Ser 728 ) was expressed and purified.
Description :
A DNA sequence encoding the human HGF ( NP_000592.3 ) precursor ( Met 1 - Ser 728 ) was expressed and purified.Hepatocyte growth factor (HGF), also known as Scatter factor, is a paracrine cellular growth, motility and morphogenic factor. Hepatocyte Growth Factor/HGF is a member of the peptidase S1 family, and is derived from a single chain precursor of 728 amino acid residues containing 4 kringle domains, 1PAN domain and 1peptidase S1 domain. The synthesized single chain of HGF is further processed into a bioactive heterodimer composed of the 69 kDa α-subunit and the 34 kDa β-subunit by a serine protease. Hepatocyte Growth Factor/HGF has no detectable protease activity. Alternative splicing of its gene produces multiple transcript variants encoding different isoforms. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, as well as haemopoietic progenitor cells. Hepatocyte Growth Factor/HGF regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the c-Met receptor. Hepatocyte Growth Factor/HGF may also play an important role as a paracrine or endocrine mediator through an epithelial-mesenchymal interaction in wound-healing, tissue or organ regeneration, morphogenesis and carcinogenesis.
Source :
CHO stable cells
Form :
Lyophilized from sterile PBS , pH 7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Purity :
>93 % as determined by SDS-PAGE
Storage :
Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
UniProt ID :
P14210
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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