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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Fms-Related Tyrosine Kinase 4, GST-tagged
catalog :
FLT4-548H
product information
Cat :
FLT4-548H
Product Name :
Recombinant Human Fms-Related Tyrosine Kinase 4, GST-tagged
Brand :
Creative Biomart
gene symbal :
FLT4
gene name :
Fms-related tyrosine kinase 4
Synonyms :
Fms-Related Tyrosine Kinase 4; Flt-4; Fms-related tyrosine kinase 4; FLT-4
Product Overview :
Recombinant human VEGFR3 was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=82kDa.
Description :
Recombinant human VEGFR3 was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=82kDa.The FLT-4 cDNA encodes a 1298 amino acid (aa) residue precursor protein with a 23 aa residue signal peptide. Mature VEGFR-3/FLT-4 is composed of a 751 aa residue extracellular domain, a 22 aa transmembrane domain and a 482 aa residue cytoplasmic domain. Both VEGF family members VEGF-C and VEGF-D have been shown to bind and activate VEGFR-3/FLT-4. The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. All three VEGF receptors belong to the class III subfamily of receptor tyrosine kinases (RTKs) characterised by the seven immunoglobulin like loops in the extracellular domain. The expression of VEGFR-1 to -3 is almost exclusively restricted to hematopoietic precursor cells, vascular and lymphatic endothelial cells and to the monocyte/macrophage lineage. They play key roles in vasculogenesis, hematopoiesis, angiogenesis and lymphangiogenesis.
Source :
Sf9 insect cells using baculovirus
Purity :
10 ug.
UniProt ID :
P35916
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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