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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human EIF4E protein
catalog :
EIF4E-2050H
product information
Cat :
EIF4E-2050H
Product Name :
Recombinant Human EIF4E protein
Brand :
Creative Biomart
gene symbal :
EIF4E
gene name :
eukaryotic translation initiation factor 4E
Synonyms :
EIF4E; eukaryotic translation initiation factor 4E; CBP; EIF4F; EIF4E1; EIF4EL1; MGC111573; eIF-4E; OTTHUMP00000219701; OTTHUMP00000219702; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; eIF-4F 25 kDa subunit; mRNA cap-binding protein; eukaryotic translation initiation factor 4E-like 1
Product Overview :
Recombinant human Protein synthesis initiation factor 4E was produced inE.coli,28 kDa.
Description :
Recombinant human Protein synthesis initiation factor 4E was produced inE.coli,28 kDa.Protein synthesis initiation factor 4E (eIF4E) is a mRNA Cap-binding protein involved in an early rate limiting step in the initiation of protein synthesis. eIF4E undergoes phosphorylation at Ser209 in response to growth factors and other extracellular stimuli. This reaction is thought to be catalyzed in cells by the mitogen-activated protein (MAP) kinase-interacting kinases (Mnk"s) and an insulin-stimulated cytosolic protamine kinase which is activated by members of the MAP kinase family. In addition, eIF4E undergoes phosphorylation at Thr210 following incubation with cPK. In cells, eIF4E occurs as a complex with inhibitory binding proteins (4EBP) and as part of the eIF4F complex which also contains eIF4A and eIF4G. In response to insulin and other extracellular stimuli, eIF4E is activated and recruited to the eIF4F complex following its dissociation from the inhibitory 4EBP. Over-expression of eIF4E leads to cell transformation and tumorigenesis.
Source :
E coli
Purity :
90% by SDS-PAGE.
Storage :
Maintain preparations in aliquots at -70 C. Avoid repeated thawing.
UniProt ID :
P06730
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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