This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Chemokine (C-X3-C Motif) Ligand 1
catalog :
CX3CL1-123H
product information
Cat :
CX3CL1-123H
Product Name :
Recombinant Human Chemokine (C-X3-C Motif) Ligand 1
Brand :
Creative Biomart
gene symbal :
CX3CL1
gene name :
chemokine (C-X3-C motif) ligand 1
Synonyms :
CX3CL1; chemokine (C-X3-C motif) ligand 1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);
Product Overview :
Recombinant Human Fractalkine encoding the extracellular domain of human fractalkine (aa residues 1 - 339 ) with KQNHHHHHH added to the carboxy-terminus was inserted into an expression vector and expressed in aNSO cell line.
Description :
Recombinant Human Fractalkine encoding the extracellular domain of human fractalkine (aa residues 1 - 339 ) with KQNHHHHHH added to the carboxy-terminus was inserted into an expression vector and expressed in aNSO cell line.Fractalkine (FKN) is a transmembrane mucin-chemokine hybrid molecule expressed on activated endothelium that mediates attachment and firm adhesion of T cells, monocytes and NK cells. FKN plays an important proinflammatory role in rheumatoid arthritis (RA) pathogenesis as characterized by induction of synovial angiogenesis, chemotaxis, activation of monocytes and T cells as well as the stimulation of proliferation and synthesis of matrix degrading enzymes (matrix metalloproteinases, MMP) in synovial fibroblasts. Fractalkine thus may represent a novel target molecule for therapeutic intervention in RA. FKN is also an essential biomarker for predicting the prognosis of patients with colorectal cancer (CRC).
Source :
NSO Cells
Purity :
97% by SDS Page and analyzed by silver stain.
UniProt ID :
P78423
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
questions and comments