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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Cytotoxic T-lymphocyte-associated Protein 4, Fc-His
catalog :
CTLA4-1598H
product information
Cat :
CTLA4-1598H
Product Name :
Recombinant Human Cytotoxic T-lymphocyte-associated Protein 4, Fc-His
Brand :
Creative Biomart
gene symbal :
CTLA4
gene name :
Ctla4 cytotoxic T-lymphocyte-associated protein 4
Synonyms :
CD; GSE; GRD4; ICOS; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ipilimumab; Yervoy; 477202-00-9; Ticilimumab (= tremelimumab); 745013-59-6
Product Overview :
Recombinant human CTLA-4 encoding amino acid residue 37-161 of the extracellular domain was fused to the Fc region of human IgG1 with six his residues added at the carboxy-terminus, cloned into a suitable expression vector and was expressed inSf 21 cells.
Description :
Recombinant human CTLA-4 encoding amino acid residue 37-161 of the extracellular domain was fused to the Fc region of human IgG1 with six his residues added at the carboxy-terminus, cloned into a suitable expression vector and was expressed inSf 21 cells.CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment.
Source :
Sf 21 Insect Cells
Purity :
90% by SDS Page and analyzed by silver stain
UniProt ID :
P16410
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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