This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human CSNK2A2
catalog :
CSNK2A2-169H
product information
Cat :
CSNK2A2-169H
Product Name :
Recombinant Human CSNK2A2
Brand :
Creative Biomart
gene symbal :
CSNK2A2
gene name :
casein kinase 2, alpha prime polypeptide
Synonyms :
CSNK2A2; casein kinase 2, alpha prime polypeptide; casein kinase II subunit alpha; CSNK2A1; CK II alpha; CK2A2; FLJ43934
Product Overview :
Recombinant protein production has become an essential tool for providing the necessary amounts of a protein of interest to either research or therapy by providing adequate amounts of proteins for studying protein structure and function. Moreover, scaled-up facilities produce recombinant vaccines, hormones, antibodies, growth factors, blood components, and enzymes.
Description :
Casein kinase 2 (CK2) is a ubiquitous pleiotropic proliferation-associated serine/threonine protein kinase. The enzyme is probably present in all eukaryotic cells, implying that it has fundamental cellular functions. Similar to protein kinase A, CK2 is a tetramer containing 2 α-prime subunits (or one of each) and 2β-subunits. The subunit fills a regulatory role in the holoenzyme. The catalytic a-subunit corresponds to the C-subunit of PKA, the non-catalytic-subunit is unique and differs from the Rsubunit of PKA in all known features. The α-prime subunits are the catalytic subunits with distinct sequences and are encoded by different genes. Whereas the CK2 α-subunit is found ubiquitously in all cells and organs the CK2 α-prime subunit is preferentially found in brain and testis. Recently it was shown that theα-subunit is trifunctional: (i) it confers stability to the holoenzyme, (ii) it increases enzyme activity, and (iii) it determines substrate specificity. Disruption of the CK2 alpha prime gene in mice results in oligospermia and globozoospermia. Thus, the CK2 alpha prime gene may be a candidate gene for inherited abnormalities of sperm morphogenesis The human recombinant protein kinase CK2 was expressed in E. coli as a N-MBP fusion protein.
Source :
E coli
Form :
Supplied in 20 mM Tris-HCl pH 7.4, 200 mM NaCl, 1 mM EDTA, and 2 mM DTT.
Purity :
99% by SDS-PAGE.
Storage :
Quality guaranteed for 12 months, Store at -80℃. Avoid freeze / thaw cycles.
UniProt ID :
P19784
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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