This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human CDK8, His-tagged
catalog :
CDK8-08H
product information
Cat :
CDK8-08H
Product Name :
Recombinant Human CDK8, His-tagged
Brand :
Creative Biomart
gene symbal :
CDK8
gene name :
cyclin-dependent kinase 8
Synonyms :
CDK8; cyclin-dependent kinase 8; K35; protein kinase K35; CDK8 protein kinase; mediator complex subunit CDK8; cell division protein kinase 8; mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075
Product Overview :
Recombinant Human Cyclin-Dependent Kinase 8 is expressed inE. colias a full-length protein fused to a proprietary 16-Kd tag (a 6xHis tag is located at the very N-terminal end). CDK8 is purified by proprietary chromatographic techniques.
Description :
Recombinant Human Cyclin-Dependent Kinase 8 is expressed inE. colias a full-length protein fused to a proprietary 16-Kd tag (a 6xHis tag is located at the very N-terminal end). CDK8 is purified by proprietary chromatographic techniques.CDK8 (cyclin-dependent kinase 8; protein kinase K35; CDK8 protein kinase; cell division protein kinase 8; K35) is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the "Mediator-like" protein complexes and the basal transcription machinery.
Source :
Escherichia Coli
Purity :
Greater than 90% as determined by SDS-PAGE.
Storage :
Store at 4 C if entire vial will be used within 1-2 weeks. Store, frozen at -20 C for longer periods of time. Avoid multiple freeze-thaw cycles.
UniProt ID :
P49336
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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