This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human CD40LG, FLAG-tagged
catalog :
CD40LG-193H
product information
Cat :
CD40LG-193H
Product Name :
Recombinant Human CD40LG, FLAG-tagged
Brand :
Creative Biomart
gene symbal :
CD40LG
gene name :
CD40 ligand
Synonyms :
CD40LG; CD40 ligand; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40-L; CD40 antigen ligand; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; tu
Product Overview :
Recombinant Human CD40LG(aa 116-261) fussed with mouse ACRP30headless (aa 18-111) and a FLAG-tag at N-terminal was expressed in CHO cells.
Description :
Recombinant Human CD40LG(aa 116-261) fussed with mouse ACRP30headless (aa 18-111) and a FLAG-tag at N-terminal was expressed in CHO cells.It is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, 5 1 integrin and IIb 3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells (TFH cells). On TFH cells, CD154 promotes B cell maturation and function by engaging CD40 on the B cell surface and therefore facilitating cell-cell communication. A defect in this gene results in an inability to undergo immunoglobulin class switching and is associated with hyper IgM syndrome. Absence of CD154 also stops the formation of germinal centers and therefore prohibiting antibody affinity maturation, an important process in the adaptive immune system.
Source :
CHO cells
Form :
Lyophilized. Contains PBS
Purity :
95% (SDS-PAGE)
Concentration :
0.1mg/ml after reconstitution.
Storage :
Short Term Storage +4 centigrade;Long Term Storage -20 centigrade.
UniProt ID :
P29965
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
questions and comments