protein

Recombinant Human Soluble CD4 Molecule

CD4-99H

Recombinant Human Soluble CD4 Molecule

Creative Biomart

CD4

CD4 molecule

CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3;

Recombinant Human sCD4 produced inBaculovirusis a single, glycosylated polypeptide chain containing 365 amino acids and having a non glycosilated molecular mass of 45 kDa. As a result of glycosilation the sCD4 migrates as a 46 kDa protein on standard SDS-PAGE. Detected By Western Immune Blots anti CD4 monoclonal antibody. The sCD4 is purified by proprietary chromatographic techniques.

Recombinant Human sCD4 produced inBaculovirusis a single, glycosylated polypeptide chain containing 365 amino acids and having a non glycosilated molecular mass of 45 kDa. As a result of glycosilation the sCD4 migrates as a 46 kDa protein on standard SDS-PAGE. Detected By Western Immune Blots anti CD4 monoclonal antibody. The sCD4 is purified by proprietary chromatographic techniques.CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cells with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.

Baculovirus

Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

sCD4 Human Recombinant although stable at 14 C for 1 week, should be stored desiccated below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

P01730