This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human CASP3, His-tagged
catalog :
CASP3-36H
product information
Cat :
CASP3-36H
Product Name :
Recombinant Human CASP3, His-tagged
Brand :
Creative Biomart
gene symbal :
CASP3
gene name :
caspase 3, apoptosis-related cysteine peptidase
Synonyms :
CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; Apopain; CPP-32; EC 3.4.22.56; Yama; procaspase3; Cysteine protease CPP32; PARP cleavage protease; SREBP cleavage activity 1; Yama protein; caspase 3, apoptosis-related cysteine protease
Product Overview :
Recombinant Human CASP3 produced in E.coli is a double, non-glycosylated, polypeptide chain cotaning 258 amino acids and having a molecular mass of 29.7 kDa. The Caspase-3 is fused to His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Description :
Recombinant Human CASP3 produced in E.coli is a double, non-glycosylated, polypeptide chain cotaning 258 amino acids and having a molecular mass of 29.7 kDa. The Caspase-3 is fused to His-Tag at C-terminus and purified by proprietary chromatographic techniques.CASP3 is part of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspase-3 enzyme results in the execution-phase of cell apoptosis/programmed cell death. Caspase 3 has been called the henchman that goes around and executes the cell. Caspase3 exists as an inactive proenzyme which undergoes proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CSN-mediated deneddylation is regulated by active CASP3. CASP-3 cleavage of RAD51 results in a functional decrease in RAD51 strand exchange activity and inhibition of caspase 3 activity increases RAD51 protein levels.
Source :
Escherichia Coli
Purity :
Greater than 90.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
UniProt ID :
P42574
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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