This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human APPL1, His-tagged
catalog :
APPL1-1001H
product information
Cat :
APPL1-1001H
Product Name :
Recombinant Human APPL1, His-tagged
Brand :
Creative Biomart
gene symbal :
APPL1
gene name :
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Synonyms :
APPL1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; DCC-interacting protein 13-alpha; APPL; dip13-alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adapter protein containing PH domain, PTB domain an
Product Overview :
Recombinant Human APPL1 was produced in E.coli containing 709 AA, N-terminal His-tag and the protease cleavage site, 31 extra AA.
Description :
Recombinant Human APPL1 was produced in E.coli containing 709 AA, N-terminal His-tag and the protease cleavage site, 31 extra AA.APPL1, an adaptor protein containing an NH2-terminal Bin/Amphiphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain and a COOH-terminal phosphotyrosine binding (PTB) domain, was originally identified as an interacting partner of Akt in a yeast two-hybrid assay using Akt2 as a bait. APPL1 binds to a number of cell surface receptors (TrkA, DCC, adiponectin, FSH) and intracellular signaling molecules (small GTPase Rab5, GIPC and inositol 5- phosphatase, suggesting that APPL1 may act as a common relay to coordinate diverse signaling cascades. APPL1 potentiates insulin-mediated Akt activation by counteracting the effect of the Akt inhibitor TRB3.
Source :
EColi
Form :
Filtered (0.22 μm) and lyophilized in 1 mg/mL in PBS.
Purity :
98%.
Storage :
Store lyophilized protein at -20 C. Lyophilized protein remains stable until the expiry date when stored at -20 C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80 C for long term storage. Reconstituted protein can be stored at 4 C for a limited period of time; it does not show any change after two weeks at 4 C.
UniProt ID :
Q9UKG1
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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