This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human AKT1 Protein, His-tagged
catalog :
AKT1-14H
product information
Cat :
AKT1-14H
Product Name :
Recombinant Human AKT1 Protein, His-tagged
Brand :
Creative Biomart
gene symbal :
AKT1
gene name :
RAC-alpha serine/threonine-protein kinase
Synonyms :
AKT 1; AKT 2; AKT 3; AKT1; AKT2; AKT3; C AKT; CAKT; DKFZP434N0250; v-akt murine thymoma viral oncogene homolog 1; Murine thymoma viral (v akt) homolog 2; murine thymoma viral (v akt) oncogene homolog 1; Murine thymoma viral (vakt) oncogene homolog 1; PKB Akt; PKB alpha; PKB; PKB beta; PKBalpha; PKBBETA; PKBG; PRKBA; PRKBB; PRKBG; Protein kinase Akt 2; Protein kinase Akt 3; Protein kinase B; Protein kinase B beta; Protein kinase B gamma; RAC alpha; RAC alpha serine/threonine protein kinase; RAC; RAC beta; RAC beta serine/threonine protein kinase; RAC gamma; RAC gamma serine/threonine protein kinase; RAC PK alpha; RAC PK beta; RAC PK gamma; Rac protein kinase alpha; Rac protein kinase beta; RAC Serine/Threonine Protein Kinase; Serine threonine protein kinase Akt 3; STK 2; STK2; V AKT Murine Thymoma Viral Oncogene Homolog 1; v akt murine thymoma viral oncogene homolog 2; v akt murine thymoma viral oncogene homolog 3; VAKT Murine Thymona Viral Oncogene 1
Product Overview :
Recombinant Human AKT1 produced inSF9is a glycosylated, polypeptide chain containing 481 amino acids and having a molecular mass of 60 KD. This protein is the full-length form of the protein with a N-terminal His-tag. AKT1 is purified by proprietary chromatographic techniques.
Description :
Recombinant Human AKT1 produced inSF9is a glycosylated, polypeptide chain containing 481 amino acids and having a molecular mass of 60 KD. This protein is the full-length form of the protein with a N-terminal His-tag. AKT1 is purified by proprietary chromatographic techniques.The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
Source :
Baculovirus, SF9 insect cells
Purity :
Greater than 95% as determined by SDS-PAGE. Mass spectrometry of tryptic digest products for identity determination.
Storage :
Store at 4 C if entire vial will be used within 1-2 weeks. Store, frozen at -20 C- -80 C for longer periods of time. Avoid multiple freeze-thaw cycles.
UniProt ID :
P31749
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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