product summary
company name :
Cosmo Bio
product type :
antibody
product name :
Anti TDP-43, phospho Ser409/410
catalog :
CAC-TIP-PTD-M01
quantity :
50UL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11-9
reactivity :
human, mouse, Caenorhabditis elegans
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; Caenorhabditis elegans; fig 9d
Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig ex1e
Falcon B, Zivanov J, Zhang W, Murzin A, Garringer H, Vidal R, et al. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature. 2019;568:420-423 pubmed publisher
  • ELISA; mouse; 1:500; loading ...; fig 3h
Schludi M, Becker L, Garrett L, Gendron T, Zhou Q, Schreiber F, et al. Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. Acta Neuropathol. 2017;134:241-254 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s6a
Becker L, Huang B, Bieri G, Ma R, Knowles D, Jafar Nejad P, et al. Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. Nature. 2017;544:367-371 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 4a
Wobst H, Wesolowski S, Chadchankar J, Delsing L, Jacobsen S, Mukherjee J, et al. Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro. Front Mol Neurosci. 2017;10:46 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:2000; fig s13
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
  • western blot; human
Smolek T, Madari A, Farbáková J, Kandrac O, Jadhav S, Cente M, et al. Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment. J Comp Neurol. 2016;524:874-95 pubmed publisher
company information
Cosmo Bio
Toyo-Ekimae Bldg., 2-20, Toyo 2-Chome, Koto-ku, Tokyo 135-0016
http://www.cosmobio.co.jp
03-5632-9600
headquarters: Japan