product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Presenilin 2 (D30G3) Rabbit mAb
catalog :
9979
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D30G3
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig s7f
Luo R, Fan Y, Yang J, Ye M, Zhang D, Guo K, et al. A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. Signal Transduct Target Ther. 2021;6:325 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s3f
Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. J Clin Invest. 2019;129:820-833 pubmed publisher
  • western blot; human; fig s2
Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  • western blot; human
Marinangeli C, Tasiaux B, Opsomer R, Hage S, Sodero A, Dewachter I, et al. Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex. J Biol Chem. 2015;290:7169-84 pubmed publisher
  • western blot; human; loading ...; fig 6b
Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed publisher
Ann E, Kim H, Seo M, Mo J, Kim M, Yoon J, et al. Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein. J Biol Chem. 2012;287:36814-29 pubmed publisher
product information
SKU :
9979S
Product-Name :
Presenilin 2 (D30G3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23 (CTF)
Host :
Rabbit
Target :
Presenilin-2
Primary-Protein :
PSEN2
Alt-Names :
AD3L,AD3LP,AD4,AD5,Alzheimer s disease 3-like,E5-1,PS-2,PS2,PSEN2,PSN2,PSNL2,Presenilin-2,Presenilin-2 CTF subunit,Presenilin-2 NTF subunit,STM-2,STM2,presenilin 2 (Alzheimer disease 4)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.