product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb (PE Conjugate)
catalog :
9978
clonality :
monoclonal
host :
rabbit
conjugate :
PE
clone name :
5A1E
reactivity :
human, mouse, rat
application :
flow cytometry
citations: 46
Reference
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Lopez M, Kopec A, Joshi N, Geddings J, Cline H, Towery K, et al. Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. Toxicol Sci. 2014;141:453-64 pubmed publisher
Shimizu K, Uematsu A, Imai Y, Sawasaki T. Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion. FEBS Lett. 2014;588:3030-7 pubmed publisher
Kolokoltsova O, Grant A, Huang C, Smith J, Poussard A, Tian B, et al. RIG-I enhanced interferon independent apoptosis upon Junin virus infection. PLoS ONE. 2014;9:e99610 pubmed publisher
Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed publisher
Bailey K, Rahimi Balaei M, Mannan A, Del Bigio M, Marzban H. Purkinje cell compartmentation in the cerebellum of the lysosomal Acid phosphatase 2 mutant mouse (nax - naked-ataxia mutant mouse). PLoS ONE. 2014;9:e94327 pubmed publisher
Moros A, Rodriguez V, Saborit Villarroya I, Montraveta A, Balsas P, Sandy P, et al. Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma. Leukemia. 2014;28:2049-59 pubmed publisher
Li Q, Zhang Y, El Naggar A, Xiong S, Yang P, Jackson J, et al. Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors. Mol Cancer Res. 2014;12:901-11 pubmed publisher
Bleil J, Maier R, Hempfing A, Schlichting U, Appel H, Sieper J, et al. Histomorphologic and histomorphometric characteristics of zygapophyseal joint remodeling in ankylosing spondylitis. Arthritis Rheumatol. 2014;66:1745-54 pubmed publisher
Youn J, Shim H, Lee J, Ji A, Oh J, Hong N, et al. Detailed pathologic evaluation on endomyocardial biopsy provides long-term prognostic information in patients with acute myocarditis. Cardiovasc Pathol. 2014;23:139-44 pubmed publisher
Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed publisher
Aiello V, Moreno Asso A, Servitja J, Martin M. Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue. Exp Cell Res. 2014;322:236-48 pubmed publisher
Kitajima M, Dolmans M, Donnez O, Masuzaki H, Soares M, Donnez J. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil Steril. 2014;101:1031-7 pubmed publisher
Qu S, Wang K, Xue H, Wang Y, Wu R, Liu C, et al. Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014;8:311-22 pubmed publisher
Wang H, Zhang Z, Huang J, Zhang P, Xiong N, Wang T. The contribution of Cdc2 in rotenone-induced G2/M arrest and caspase-3-dependent apoptosis. J Mol Neurosci. 2014;53:31-40 pubmed publisher
Murakami T, Takigawa N, Ninomiya T, Ochi N, Yasugi M, Honda Y, et al. Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model. Lung Cancer. 2014;83:30-6 pubmed publisher
Liu T, Hou D, Zhao Q, Liu W, Zhen P, Xu J, et al. Phytoestrogen ?-Zearalanol attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells. Biomed Res Int. 2013;2013:813450 pubmed publisher
Kash J, Xiao Y, Davis A, Walters K, Chertow D, Easterbrook J, et al. Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice. Free Radic Biol Med. 2014;67:235-47 pubmed publisher
Foreman K, Jesse J, Kuo P, Gupta G. Emetine dihydrochloride: a novel therapy for bladder cancer. J Urol. 2014;191:502-9 pubmed publisher
Emmanouilidou A, Karetsou Z, Tzima E, Kobayashi T, Papamarcaki T. Knockdown of prothymosin ? leads to apoptosis and developmental defects in zebrafish embryos. Biochem Cell Biol. 2013;91:325-32 pubmed publisher
Dzieran J, Fabian J, Feng T, Coulouarn C, Ilkavets I, Kyselova A, et al. Comparative analysis of TGF-?/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS ONE. 2013;8:e72252 pubmed publisher
Kreslavsky T, Kim H, Koralov S, Ghitza D, Buch T, Cantor H, et al. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013;210:1911-8 pubmed publisher
Li Q, He H, Zhang Y, Li X, Guo X, Huo R, et al. Phosphoinositide 3-kinase p110? mediates estrogen- and FSH-stimulated ovarian follicle growth. Mol Endocrinol. 2013;27:1468-82 pubmed publisher
Shimizu K, Sawasaki T. Nek5, a novel substrate for caspase-3, promotes skeletal muscle differentiation by up-regulating caspase activity. FEBS Lett. 2013;587:2219-25 pubmed publisher
Wu M, Wang G, Zhao Z, Liang Y, Wang H, Wu M, et al. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Mol Cancer Ther. 2013;12:1728-37 pubmed publisher
Cheng A, Jiang S, Fan C, Lo Y, Kuo C, Chen C, et al. Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents. Cancer Lett. 2013;337:218-25 pubmed publisher
Wilk C, Schildberg F, Lauterbach M, Cadeddu R, Fröbel J, Westphal V, et al. The tissue inhibitor of metalloproteinases-1 improves migration and adhesion of hematopoietic stem and progenitor cells. Exp Hematol. 2013;41:823-831.e2 pubmed publisher
Bajic D, Commons K, Soriano S. Morphine-enhanced apoptosis in selective brain regions of neonatal rats. Int J Dev Neurosci. 2013;31:258-66 pubmed publisher
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Brobeil A, Bobrich M, Tag C, Wimmer M. PTPIP51 in protein interactions: regulation and in situ interacting partners. Cell Biochem Biophys. 2012;63:211-22 pubmed publisher
Knudsen A, Kannerup A, Grønbæk H, Dutoit S, Nyengaard J, Funch Jensen P, et al. Quantitative histological assessment of hepatic ischemia-reperfusion injuries following ischemic pre- and post-conditioning in the rat liver. J Surg Res. 2013;180:e11-20 pubmed publisher
Debrincat M, Josefsson E, James C, Henley K, Ellis S, Lebois M, et al. Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. Blood. 2012;119:5850-8 pubmed publisher
Heindl M, Händel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, et al. Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome. Gastroenterology. 2012;142:1093-1096.e6 pubmed publisher
Miki H, Uehara N, Kimura A, Sasaki T, Yuri T, Yoshizawa K, et al. Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells. Int J Oncol. 2012;40:1020-8 pubmed publisher
de Andrea C, Wiweger M, Bovee J, Romeo S, Hogendoorn P. Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation. Virchows Arch. 2012;460:95-102 pubmed publisher
product information
SKU :
9978S
Product-Name :
Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb (PE Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Casp3 (Asp175) cleaved
Primary-Protein :
Casp3
Alt-Names :
Apopain,CASP-3,CASP3,CPP-32,CPP32,CPP32B,Caspase-3,Caspase-3 subunit p12,Caspase-3 subunit p17,Cysteine protease CPP32,PARP cleavage protease,Protein Yama,SCA-1,SREBP cleavage activity 1,Yama,caspase 3, apoptosis-related cysteine peptidase,caspase 3, apoptosis-related cysteine protease,procaspase3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.