product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
O-GlcNAc (CTD110.6) Mouse mAb
catalog :
9875
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CTD110.6
reactivity :
human, mouse
application :
western blot, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5h
  • western blot; human; 1:1000; loading ...; fig 5c
Shang M, Yang H, Yang R, Chen T, Fu Y, Li Y, et al. The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation. Nat Commun. 2021;12:1940 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4e
Bott A, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang Y, et al. Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep. 2019;29:1287-1298.e6 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 5g
Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya M, Wang X, et al. O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis. J Clin Invest. 2018;128:4924-4937 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4i
Gubbiotti M, Seifert E, Rodeck U, Hoek J, Iozzo R. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. J Biol Chem. 2018;293:16940-16950 pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Zhang W, Wu M, Kim T, Jariwala R, Garvey W, Luo N, et al. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance. Diabetes. 2016;65:2380-91 pubmed publisher
  • western blot; human; fig 2
Yang Y, Kim D, Seo Y, Park D, Jang H, Choi S, et al. Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling. Oncotarget. 2015;6:12529-42 pubmed
CAMPBELL S, Mesaros C, Izzo L, AFFRONTI H, Noji M, Schaffer B, et al. Glutamine deprivation triggers NAGK-dependent hexosamine salvage. elife. 2021;10: pubmed publisher
Hu C, Tien S, Hsieh P, Jeng Y, Chang M, Chang Y, et al. High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells. Cell Metab. 2019;29:1334-1349.e10 pubmed publisher
Sager R, Woodford M, Backe S, Makedon A, Baker Williams A, DiGregorio B, et al. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Rep. 2019;26:1344-1356.e5 pubmed publisher
Wang D, Hu X, Lee S, Chen F, Jiang K, Tu Z, et al. Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation. JACC Basic Transl Sci. 2018;3:350-362 pubmed publisher
Tourzani D, Paudel B, Miranda P, Visconti P, Gervasi M. Changes in Protein O-GlcNAcylation During Mouse Epididymal Sperm Maturation. Front Cell Dev Biol. 2018;6:60 pubmed publisher
Scott N, Giogha C, Pollock G, Kennedy C, Webb A, Williamson N, et al. The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD). J Biol Chem. 2017;292:17337-17350 pubmed publisher
Chen Y, Zhao Y, Dai C, Liang Z, Run X, Iqbal K, et al. Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces A? level and microglia activation in the brains of 3xTg-AD mice. Exp Neurol. 2014;261:610-9 pubmed publisher
Xu Q, Yang C, Du Y, Chen Y, Liu H, Deng M, et al. AMPK regulates histone H2B O-GlcNAcylation. Nucleic Acids Res. 2014;42:5594-604 pubmed publisher
Mitra R, Goodman O, Le T. Enhanced detection of metastatic prostate cancer cells in human plasma with lipid bodies staining. BMC Cancer. 2014;14:91 pubmed publisher
Xu C, Liu G, Liu X, Wang F. O-GlcNAcylation under hypoxic conditions and its effects on the blood-retinal barrier in diabetic retinopathy. Int J Mol Med. 2014;33:624-32 pubmed publisher
Yagi H, Nakagawa N, Saito T, Kiyonari H, Abe T, Toda T, et al. AGO61-dependent GlcNAc modification primes the formation of functional glycans on ?-dystroglycan. Sci Rep. 2013;3:3288 pubmed publisher
Ding F, Yu L, Wang M, Xu S, Xia Q, Fu G. O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2. Amino Acids. 2013;45:339-49 pubmed publisher
product information
SKU :
9875S
Product-Name :
O-GlcNAc (CTD110.6) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
All
Applications :
Western blot
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Mouse
Target :
O-GlcNAc
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.