| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 2d, 7e
| Singh S, Abu Zaid A, Lin W, Low J, Abdolvahabi A, Jin H, et al. 17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma. iScience. 2021;24:101996 pubmed publisher |
- flow cytometry; mouse; loading ...; fig 2n
| Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3d
- ChIP-Seq; mouse; loading ...; fig 3e
| Eckert M, Coscia F, Chryplewicz A, Chang J, Hernandez K, Pan S, et al. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019;: pubmed publisher |
- chromatin immunoprecipitation; mouse; ; loading ...; fig 4d
| El Brolosy M, Kontarakis Z, Rossi A, Kuenne C, Günther S, Fukuda N, et al. Genetic compensation triggered by mutant mRNA degradation. Nature. 2019;: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 5e
| McBrayer S, Olenchock B, DiNatale G, Shi D, Khanal J, Jennings R, et al. Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase. Proc Natl Acad Sci U S A. 2018;115:E3741-E3748 pubmed publisher |
| Andricovich J, Perkail S, Kai Y, Casasanta N, Peng W, Tzatsos A. Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. Cancer Cell. 2018;33:512-526.e8 pubmed publisher |
- chromatin immunoprecipitation; mouse; loading ...; fig 5f
| Wang B, Fu X, Zhu M, Du M. Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation. J Mol Cell Biol. 2017;9:338-349 pubmed publisher |
- western blot; human; fig s5a
| Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, et al. Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature. 2017;542:484-488 pubmed publisher |
- ChIP-Seq; human; loading ...; fig s3b
| Göllner S, Oellerich T, Agrawal Singh S, Schenk T, Klein H, Rohde C, et al. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat Med. 2017;23:69-78 pubmed publisher |
- ChIP-Seq; mouse; loading ...; tbl 2
- ChIP-Seq; human; loading ...; tbl 2
| Busby M, Xue C, Li C, Farjoun Y, Gienger E, Yofe I, et al. Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq. Epigenetics Chromatin. 2016;9:49 pubmed |
- ChIP-Seq; human; loading ...; fig 1i
| Platt J, Salama R, Smythies J, Choudhry H, Davies J, Hughes J, et al. Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters. EMBO Rep. 2016;17:1410-1421 pubmed |
- chromatin immunoprecipitation; human; loading ...; fig 5a
| Zhou A, Lin K, Zhang S, Chen Y, Zhang N, Xue J, et al. Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22. Nat Cell Biol. 2016;18:954-966 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig s1
| Dhawan S, Dirice E, Kulkarni R, Bhushan A. Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication. Diabetes. 2016;65:1208-18 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig 3
| Benitz S, Regel I, Reinhard T, Popp A, Schäffer I, Raulefs S, et al. Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells. Oncotarget. 2016;7:11424-33 pubmed publisher |
- chromatin immunoprecipitation; human; fig 1
| Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed publisher |
- chromatin immunoprecipitation; rat; fig 3
| Laumet G, Garriga J, Chen S, Zhang Y, Li D, Smith T, et al. G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. Nat Neurosci. 2015;18:1746-55 pubmed publisher |
- immunohistochemistry - paraffin section; fruit fly ; 1:200; loading ...; fig s1b
- western blot; fruit fly ; 1:1000; loading ...; fig s1a
| Tarayrah L, Li Y, Gan Q, Chen X. Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity. Biol Open. 2015;4:1518-27 pubmed publisher |
- western blot; human; fig 6g
| Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, et al. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015;35:3633-45 pubmed publisher |
| Sin H, Kartashov A, Hasegawa K, Barski A, Namekawa S. Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline. BMC Biol. 2015;13:53 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig s8
| Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed publisher |
- chromatin immunoprecipitation; rat
| Zhang Y, Laumet G, Chen S, Hittelman W, Pan H. Pannexin-1 Up-regulation in the Dorsal Root Ganglion Contributes to Neuropathic Pain Development. J Biol Chem. 2015;290:14647-55 pubmed publisher |
- immunocytochemistry; human; fig 7
- western blot; human; fig 6
| Hendriks I, Treffers L, Verlaan de Vries M, Olsen J, Vertegaal A. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. Cell Rep. 2015;10:1778-1791 pubmed publisher |
- chromatin immunoprecipitation; human
| Yang S, Zhang J, Zhang Y, Wan X, Zhang C, Huang X, et al. KDM1A triggers androgen-induced miRNA transcription via H3K4me2 demethylation and DNA oxidation. Prostate. 2015;75:936-46 pubmed publisher |
- chromatin immunoprecipitation; human; fig 3
| Matsuda Y, Kobayashi Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M. Epigenetic heterogeneity in HIV-1 latency establishment. Sci Rep. 2015;5:7701 pubmed publisher |
- chromatin immunoprecipitation; human; 2 ugs
| Naganuma K, Hatta M, Ikebe T, Yamazaki J. Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma. BMC Cancer. 2014;14:988 pubmed publisher |
- immunohistochemistry; mouse; fig 5
| Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, et al. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014;5:5425 pubmed publisher |
- chromatin immunoprecipitation; human; fig 3
| Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, et al. Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. elife. 2014;3: pubmed publisher |
- chromatin immunoprecipitation; mouse
| Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, et al. Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice. J Immunol. 2014;192:5012-22 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig st13
| Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
| Chen Y, Kao S, Wang H, Yang M. Histone modification patterns correlate with patient outcome in oral squamous cell carcinoma. Cancer. 2013;119:4259-67 pubmed publisher |
| Oser M, Sabet A, Gao W, Chakraborty A, Schinzel A, Jennings R, et al. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis. Genes Dev. 2019;33:1718-1738 pubmed publisher |
| Larson J, Kasper L, Paugh B, Jin H, Wu G, Kwon C, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. 2019;35:140-155.e7 pubmed publisher |
| Uchiyama R, Kupkova K, Shetty S, Linford A, Pray Grant M, Wagar L, et al. Histone H3 lysine 4 methylation signature associated with human undernutrition. Proc Natl Acad Sci U S A. 2018;115:E11264-E11273 pubmed publisher |
| Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher |
| Sun H, Zhao X, Zhang C, Zhang Z, Lun J, Liao W, et al. MiR-455-3p inhibits the degenerate process of chondrogenic differentiation through modification of DNA methylation. Cell Death Dis. 2018;9:537 pubmed publisher |
| Agathocleous M, Meacham C, Burgess R, Piskounova E, Zhao Z, Crane G, et al. Ascorbate regulates haematopoietic stem cell function and leukaemogenesis. Nature. 2017;549:476-481 pubmed publisher |
| Gong F, Clouaire T, Aguirrebengoa M, Legube G, Miller K. Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair. J Cell Biol. 2017;216:1959-1974 pubmed publisher |
| Ohshima K, Nojima S, Tahara S, Kurashige M, Hori Y, Hagiwara K, et al. Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer. Sci Rep. 2017;7:45504 pubmed publisher |
| Xiaojun W, Yan L, Hong X, Xianghong Z, Shifeng L, Dingjie X, et al. Acetylated ?-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica. Sci Rep. 2016;6:32257 pubmed publisher |
| Mendoza Parra M, Saravaki V, Cholley P, Blum M, Billoré B, Gronemeyer H. Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification. F1000Res. 2016;5:54 pubmed publisher |
| Pandey S, Simmons G, Malyarchuk S, Calhoun T, Pruitt K. A novel MeCP2 acetylation site regulates interaction with ATRX and HDAC1. Genes Cancer. 2015;6:408-21 pubmed |
| Jakobsen J, Bagger F, Hasemann M, Schuster M, Frank A, Waage J, et al. Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq. BMC Genomics. 2015;16:46 pubmed publisher |
| Theisen E, Gajiwala S, Bearss J, Sorna V, Sharma S, JANAT AMSBURY M. Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma. BMC Cancer. 2014;14:752 pubmed publisher |
| Blattler A, Yao L, Witt H, Guo Y, Nicolet C, Berman B, et al. Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes. Genome Biol. 2014;15:469 pubmed publisher |
| Ishida S, Tanaka R, Yamaguchi N, Ogata G, Mizutani T, Kawabata K, et al. Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel. PLoS ONE. 2014;9:e99655 pubmed publisher |
| Miyata K, Yotsumoto F, Nam S, Odawara T, Manabe S, Ishikawa T, et al. Contribution of transcription factor, SP1, to the promotion of HB-EGF expression in defense mechanism against the treatment of irinotecan in ovarian clear cell carcinoma. Cancer Med. 2014;3:1159-69 pubmed publisher |
| Takahashi R, Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, et al. Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia. Cancer Sci. 2014;105:1160-9 pubmed publisher |
| Eisfeld A, Schwind S, Patel R, Huang X, Santhanam R, Walker C, et al. Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway. Sci Signal. 2014;7:ra36 pubmed publisher |
| Kim W, Bird G, Neff T, Guo G, Kerenyi M, Walensky L, et al. Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol. 2013;9:643-50 pubmed publisher |
| Chen K, Johnston J, Shao W, Meier S, Staber C, Zeitlinger J. A global change in RNA polymerase II pausing during the Drosophila midblastula transition. elife. 2013;2:e00861 pubmed publisher |
| Paige S, Thomas S, Stoick Cooper C, Wang H, Maves L, Sandstrom R, et al. A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell. 2012;151:221-32 pubmed publisher |
| Thurman R, Rynes E, Humbert R, Vierstra J, Maurano M, Haugen E, et al. The accessible chromatin landscape of the human genome. Nature. 2012;489:75-82 pubmed publisher |
| Peach S, Rudomin E, Udeshi N, Carr S, Jaffe J. Quantitative assessment of chromatin immunoprecipitation grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules. Mol Cell Proteomics. 2012;11:128-37 pubmed publisher |
| Hu Y, Shen Y, Conde e Silva N, Zhou D. The role of histone methylation and H2A.Z occupancy during rapid activation of ethylene responsive genes. PLoS ONE. 2011;6:e28224 pubmed publisher |
| Schmitz S, Albert M, Malatesta M, Morey L, Johansen J, Bak M, et al. Jarid1b targets genes regulating development and is involved in neural differentiation. EMBO J. 2011;30:4586-600 pubmed publisher |
| Pasini D, Malatesta M, Jung H, Walfridsson J, Willer A, Olsson L, et al. Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res. 2010;38:4958-69 pubmed publisher |
