product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Smad1 Antibody
catalog :
9743
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, brown rat, bantam
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 7a
Deng Q, Li P, Che M, Liu J, Biswas S, Ma G, et al. Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 2f
Dufton N, Peghaire C, Osuna Almagro L, Raimondi C, Kalna V, Chuahan A, et al. Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Nat Commun. 2017;8:895 pubmed publisher
  • western blot; human; loading ...; fig 1e
Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2d
Wang C, Core A, Canali S, Zumbrennen Bullough K, Ozer S, Umans L, et al. Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice. Blood. 2017;130:73-83 pubmed publisher
  • western blot; human; 1:1000; fig 2b
Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed publisher
  • western blot; mouse; loading ...; fig s5a
Jiang C, Diao F, Sang Y, Xu N, Zhu R, Wang X, et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017;13:e1006535 pubmed publisher
  • immunohistochemistry; bantam; 1:100; fig 1
  • western blot; bantam; 1:100; fig 2
Amarnath S, Agarwala S. Cell-cycle-dependent TGF?-BMP antagonism regulates neural tube closure by modulating tight junctions. J Cell Sci. 2017;130:119-131 pubmed publisher
  • western blot; mouse; fig 8
Zhao G, Zhu P, Renvoisé B, Maldonado Baez L, Park S, Blackstone C. Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology. Exp Cell Res. 2016;349:32-44 pubmed publisher
  • western blot; mouse; 1:500; fig 6
Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016;7:12503 pubmed publisher
  • immunoprecipitation; mouse; 1:100; loading ...; fig 8c
  • western blot; mouse; 1:1000; loading ...; fig 7c
Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed publisher
Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed publisher
Artigas N, Gámez B, Cubillos Rojas M, Sánchez de Diego C, Valer J, Pons G, et al. p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation. Cell Death Differ. 2017;24:2022-2031 pubmed publisher
Kim D, Kim Y, Jung Y, Kim K, Jeong J, Lee Y, et al. Orphan nuclear receptor SHP regulates iron metabolism through inhibition of BMP6-mediated hepcidin expression. Sci Rep. 2016;6:34630 pubmed publisher
Baeyens N, Larrivee B, Ola R, Hayward Piatkowskyi B, Dubrac A, Huang B, et al. Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia. J Cell Biol. 2016;214:807-16 pubmed publisher
Zieba J, Forlenza K, Khatra J, Sarukhanov A, Durán I, Rigueur D, et al. TGF? and BMP Dependent Cell Fate Changes Due to Loss of Filamin B Produces Disc Degeneration and Progressive Vertebral Fusions. PLoS Genet. 2016;12:e1005936 pubmed publisher
product information
SKU :
9743S
Product-Name :
Smad1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
58-60
Host :
Rabbit
Target :
Smad1
Primary-Protein :
Smad1
Alt-Names :
BSP-1,BSP1,JV4-1,JV41,MAD homolog 1,MAD, mothers against decapentaplegic homolog 1,MADH1,MADR1,Mad-related protein 1,Mothers against DPP homolog 1,Mothers against decapentaplegic homolog 1,SMAD 1,SMAD family member 1,SMAD, mothers against DPP homolog 1,SMAD1,TGF-beta signaling protein 1,Transforming growth factor-beta-signaling protein 1,hSMAD1,transforming growth factor-beta signaling protein 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.