product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
eIF2α Antibody
catalog :
9722S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
citations: 15
Published Application/Species/DilutionReference
  • western blot; mouse; fig 4
Ben-Sahra I, Hoxhaj G, Ricoult S, Asara J, Manning B. mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle. Science. 2016;351:728-33 pubmed publisher
  • western blot; human; fig 1
Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher
  • western blot; human; 1:1000
Xie W, Pariollaud M, Wixted W, Chitnis N, Fornwald J, Truong M, et al. Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation. PLoS ONE. 2015;10:e0119738 pubmed publisher
  • western blot; rat; 1:1000
Way S, Podojil J, Clayton B, Zaremba A, Collins T, Kunjamma R, et al. Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nat Commun. 2015;6:6532 pubmed publisher
  • western blot; human; fig 2
Sheng X, Arnoldussen Y, Storm M, Tesikova M, Nenseth H, Zhao S, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Mol Med. 2015;7:788-801 pubmed publisher
  • western blot; human; 1:1000
Sidrauski C, McGeachy A, Ingolia N, Walter P. The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. elife. 2015;4: pubmed publisher
  • western blot; human
Michel S, Canonne M, Arnould T, Renard P. Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response. Mitochondrion. 2015;21:58-68 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Miyamoto Y, Mauer A, Kumar S, Mott J, Malhi H. Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. PLoS ONE. 2014;9:e109637 pubmed publisher
  • western blot; human; 1:500
Kaehler C, Isensee J, Hucho T, Lehrach H, Krobitsch S. 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res. 2014;42:6436-47 pubmed publisher
  • western blot; human; 1:1000
Jorgensen E, Stinson A, Shan L, Yang J, Gietl D, Albino A. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer. 2008;8:229 pubmed publisher
Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, et al. Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas. J Physiol Biochem. 2016;72:281-91 pubmed publisher
Herrmann U, Sonati T, Falsig J, Reimann R, Dametto P, O'Connor T, et al. Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. PLoS Pathog. 2015;11:e1004662 pubmed publisher
Sweeney E, Fan P, Jordan V. Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells. Int J Oncol. 2014;44:1529-38 pubmed publisher
Riddle E, Campbell M, Lang B, Bierer R, Wang Y, Bagley H, et al. Intrauterine growth restriction increases TNF α and activates the unfolded protein response in male rat pups. J Obes. 2014;2014:829862 pubmed publisher
Wu M, Liu H, Fannin J, Katta A, Wang Y, Arvapalli R, et al. Acetaminophen improves protein translational signaling in aged skeletal muscle. Rejuvenation Res. 2010;13:571-9 pubmed publisher
product information
SKU :
9722S
Product-Name :
eIF2α Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
38
Host :
Rabbit
Target :
eIF2A
Primary-Protein :
eIF2A
Alt-Names :
EIF-2,EIF2,EIF2A,EIF2S1,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit alpha,IF2A,eIF-2-alpha,eIF-2A,eIF-2alpha,eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.