| Published Application/Species/Dilution | Reference |
|---|
- western blot; human; fig 3
| Ansari M, Haqqi T. Interleukin-1β induced Stress Granules Sequester COX-2 mRNA and Regulates its Stability and Translation in Human OA Chondrocytes. Sci Rep. 2016;6:27611 pubmed publisher |
- western blot; mouse; fig 4
| Ben-Sahra I, Hoxhaj G, Ricoult S, Asara J, Manning B. mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle. Science. 2016;351:728-33 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher |
- western blot; human; fig 3
| Yalon M, Tuval-Kochen L, Castel D, Moshe I, Mazal I, Cohen O, et al. Overcoming Resistance of Cancer Cells to PARP-1 Inhibitors with Three Different Drug Combinations. PLoS ONE. 2016;11:e0155711 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher |
- western blot; mouse; fig 1C
- immunocytochemistry; mouse; fig 1A
| Zismanov V, Chichkov V, Colangelo V, Jamet S, Wang S, Syme A, et al. Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 2016;18:79-90 pubmed publisher |
- western blot; rat; fig 3a
| Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6α activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher |
- western blot; human; 1:500; fig 4
| Plate L, Cooley C, Chen J, Paxman R, Gallagher C, Madoux F, et al. Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. elife. 2016;5: pubmed publisher |
- immunocytochemistry; mouse; 1:1000; fig s5
- western blot; mouse; 1:1000; fig 7
- immunohistochemistry; mouse; 1:1000; fig s6
| Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher |
- western blot; zebrafish; fig s7
| Hu M, Bai Y, Zhang C, Liu F, Cui Z, Chen J, et al. Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genet. 2016;12:e1005881 pubmed publisher |
- western blot; human; fig 1
| Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher |
- western blot; human; fig 5
| Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed publisher |
- immunohistochemistry - free floating section; mouse; fig 1e
- western blot; mouse; fig 2a
| Ostapchenko V, Chen M, Guzman M, Xie Y, Lavine N, Fan J, et al. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment. J Neurosci. 2015;35:15157-69 pubmed publisher |
| Bejaoui M, Pantazi E, De Luca V, Panisello A, Folch-Puy E, Hotter G, et al. Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. PLoS ONE. 2015;10:e0134499 pubmed publisher |
- western blot; human; fig 6
| Artero-Castro A, Pérez-Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher |
| Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed publisher |
- western blot; mouse; 1:1000
| Radford H, Moreno J, Verity N, Halliday M, Mallucci G. PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia. Acta Neuropathol. 2015;130:633-42 pubmed publisher |
| Kim D, Park M, Choi J, Lim S, Choi H, Park S. Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. Int J Biochem Cell Biol. 2015;59:41-51 pubmed publisher |
- western blot; human; fig 3,5,6,7
- western blot; mouse; fig 4,7
| So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher |
| Karner C, Esen E, Okunade A, Patterson B, Long F. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. J Clin Invest. 2015;125:551-62 pubmed publisher |
- western blot; human; 1:1000; fig 4b
| Duan H, Li Y, Lim H, Wang W. Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression. Bioorg Med Chem. 2015;23:4514-21 pubmed publisher |
| Van B, Nishi M, Komazaki S, Ichimura A, Kakizawa S, Nakanaga K, et al. Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation. FEBS Lett. 2015;589:1095-104 pubmed publisher |
- western blot; human; fig 5
| Gupta A, Hossain M, Read D, Hetz C, Samali A, Gupta S. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response. Sci Rep. 2015;5:18304 pubmed publisher |
| Deegan S, Koryga I, Glynn S, Gupta S, Gorman A, Samali A. A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy. Biochem Biophys Res Commun. 2015;456:305-11 pubmed publisher |
- western blot; human; 1:1000
| KENNEDY D, Mnich K, Samali A. Heat shock preconditioning protects against ER stress-induced apoptosis through the regulation of the BH3-only protein BIM. FEBS Open Bio. 2014;4:813-21 pubmed publisher |
| Gonzalez-Rodriguez A, Mayoral R, Agra N, Valdecantos M, Pardo V, Miquilena-Colina M, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis. 2014;5:e1179 pubmed publisher |
| Legrand N, Araud T, Conne B, Kuijpers O, Jaquier-Gubler P, Curran J. An AUG codon conserved for protein function rather than translational initiation: the story of the protein sElk1. PLoS ONE. 2014;9:e102890 pubmed publisher |
| Xiong R, Siegel D, Ross D. Quinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicity. Toxicol Appl Pharmacol. 2014;280:285-95 pubmed publisher |
| Moutaoufik M, El Fatimy R, Nassour H, Gareau C, Lang J, Tanguay R, et al. UVC-induced stress granules in mammalian cells. PLoS ONE. 2014;9:e112742 pubmed publisher |
| Deegan S, Saveljeva S, Gupta S, Macdonald D, Samali A. ER stress responses in the absence of apoptosome: a comparative study in CASP9 proficient vs deficient mouse embryonic fibroblasts. Biochem Biophys Res Commun. 2014;451:367-73 pubmed publisher |
- western blot; human; 1:1000
| Ninio-Many L, Grossman H, Levi M, Zilber S, Tsarfaty I, Shomron N, et al. MicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells. Oncoscience. 2014;1:250-61 pubmed |
| Fung G, Ng C, Zhang J, Shi J, Wong J, Piesik P, et al. Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infection. PLoS ONE. 2013;8:e79546 pubmed publisher |
| Yang Z, Xu Y, Xu L, Maccauro G, Rossi B, Chen Y, et al. Regulation of autophagy via PERK-eIF2α effectively relieve the radiation myelitis induced by iodine-125. PLoS ONE. 2013;8:e76819 pubmed publisher |
- western blot; mouse; 1,000
| Brennan G, Jimenez-Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS ONE. 2013;8:e54491 pubmed publisher |
- western blot; human; 1:1000
| Park Y, Ko J, Jang Y, Kwon Y. Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells. Neurochem Res. 2013;38:1561-71 pubmed publisher |
- western blot; human; 1:500
| Peng Y, Shi Y, Ding Z, Ke A, Gu C, Hui B, et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy. 2013;9:2056-68 pubmed publisher |
- western blot; mouse; 1:1000
| Kang E, Kwon I, Koo J, Kim E, Kim C, Lee J, et al. Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice. Apoptosis. 2013;18:1332-47 pubmed publisher |
- western blot; mouse; fig 1
| Dickhout J, Carlisle R, Jerome D, Mohammed-Ali Z, Jiang H, Yang G, et al. Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012;287:7603-14 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Henke N, Albrecht P, Pfeiffer A, Toutzaris D, Zanger K, Methner A. Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress. J Biol Chem. 2012;287:42042-52 pubmed publisher |
| Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, et al. DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. 2011;6:38 pubmed |
| Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, et al. Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas. J Physiol Biochem. 2016;72:281-91 pubmed publisher |
| Herrmann U, Sonati T, Falsig J, Reimann R, Dametto P, O'Connor T, et al. Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. PLoS Pathog. 2015;11:e1004662 pubmed publisher |
| Vacaru A, Di Narzo A, Howarth D, Tsedensodnom O, Imrie D, Cinaroglu A, et al. Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish. Dis Model Mech. 2014;7:823-35 pubmed publisher |
| Luna E, van Hulten M, Zhang Y, Berkowitz O, Lopez A, Pétriacq P, et al. Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase. Nat Chem Biol. 2014;10:450-6 pubmed publisher |
| Shiau A, Shen Y, Hsieh J, Wu C, Lee C. Scutellaria barbata inhibits angiogenesis through downregulation of HIF-1 α in lung tumor. Environ Toxicol. 2014;29:363-70 pubmed publisher |
| Sweeney E, Fan P, Jordan V. Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells. Int J Oncol. 2014;44:1529-38 pubmed publisher |
| Kalderon B, Azazmeh N, Azulay N, Vissler N, Valitsky M, Bar-Tana J. Suppression of adipose lipolysis by long-chain fatty acid analogs. J Lipid Res. 2012;53:868-78 pubmed publisher |
| Chen H, Anagnostou G, Chai A, Withers J, Morris A, Adhikaree J, et al. Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis. J Biol Chem. 2010;285:40266-81 pubmed publisher |
