| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 4b
| Tien J, Chugh S, Goodrum A, Cheng Y, Mannan R, Zhang Y, et al. AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
- western blot; human; 1:10,000; loading ...; fig 1c
| Martínez Gutiérrez A, Fernández Duran I, Marazuela Duque A, Simonet N, Yousef I, Martínez Rovira I, et al. Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1. Aging (Albany NY). 2021;13:12308-12333 pubmed publisher |
- western blot; human; loading ...; fig 4e
| Bao Y, Oguz G, Lee W, Lee P, Ghosh K, Li J, et al. EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy. Nat Commun. 2020;11:5878 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3h
| Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher |
- western blot; human; 1:3000; loading ...; fig 3e
| Park D, Cheng J, McGrath J, Lim M, Cushman C, Swanson S, et al. Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. Nat Cell Biol. 2020;22:603-615 pubmed publisher |
- chromatin immunoprecipitation; rat; 1:15; loading ...; fig 5b
| Torres Mejía E, Trumbach D, Kleeberger C, Dornseifer U, Orschmann T, Bäcker T, et al. Sox2 controls Schwann cell self-organization through fibronectin fibrillogenesis. Sci Rep. 2020;10:1984 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3b
| Coccia E, Planells Ferrer L, Badillos Rodríguez R, Pascual M, Segura M, Fernández Hernández R, et al. SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L. Cell Death Dis. 2020;11:82 pubmed publisher |
- western blot; mouse; 1:5000; loading ...; fig 4e
| Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5f, 6c
| Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2d
| Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, et al. GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling. Nat Commun. 2019;10:3882 pubmed publisher |
- western blot; mouse; loading ...; fig 2b
| Qiu J, Villa M, Sanin D, Buck M, O Sullivan D, Ching R, et al. Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Rep. 2019;27:2063-2074.e5 pubmed publisher |
- western blot; mouse; 122 ng/ml; loading ...; fig s13c
| Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher |
- western blot; human; loading ...; fig 6c
| Wang Y, Brady K, Caiello B, Ackerson S, Stewart J. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association. Life Sci Alliance. 2019;2: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1d
| Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7a
| Niu F, Liao K, Hu G, Sil S, Callen S, Guo M, et al. Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS. J Cell Biol. 2019;218:700-721 pubmed publisher |
- western blot; Xenopus laevis; loading ...; fig 1d
| Sparks J, Chistol G, Gao A, Raschle M, Larsen N, Mann M, et al. The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair. Cell. 2019;176:167-181.e21 pubmed publisher |
- western blot; mouse; loading ...; fig 8f
| Yin J, Wang Y, Chang J, Li B, Zhang J, Liu Y, et al. Apelin inhibited epithelial-mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i. Cell Death Dis. 2018;9:1031 pubmed publisher |
- western blot; Xenopus laevis; 1:2000; fig 1a
| Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed publisher |
- western blot; human; 1:1000; fig 2a
| Titone R, Zhu M, Robertson D. Insulin mediates de novo nuclear accumulation of the IGF-1/insulin Hybrid Receptor in corneal epithelial cells. Sci Rep. 2018;8:4378 pubmed publisher |
- western blot; human; loading ...; fig 7a
| Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Gonzalez M, Martin E, Anwar T, Arellano Garcia C, Medhora N, Lama A, et al. Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth. Cell Rep. 2017;18:1215-1228 pubmed publisher |
- western blot; mouse; 1:10,000; loading ...; fig 1a
| Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, et al. iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53. PLoS ONE. 2017;12:e0170391 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2f
- western blot; mouse; 1:1000; loading ...; fig 4b
| Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, et al. Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS. EMBO Mol Med. 2016;8:1421-1437 pubmed publisher |
- western blot; mouse; loading ...; fig 1b
- western blot; human; loading ...; fig 1a
| Pazienza V, Panebianco C, Rappa F, Memoli D, Borghesan M, Cannito S, et al. Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis. Epigenetics Chromatin. 2016;9:45 pubmed |
- western blot; human; 1:1000; fig 5e
| Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher |
- western blot; human; 1:1000; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher |
- western blot; human; loading ...; fig 2f
| Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed publisher |
- western blot; human; fig 6
| Duggan S, Behan F, Kirca M, Zaheer A, McGarrigle S, Reynolds J, et al. The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival. Sci Rep. 2016;6:32638 pubmed publisher |
- western blot; mouse; loading ...; fig 1b
| Gallardo Montejano V, Saxena G, Kusminski C, Yang C, McAfee J, Hahner L, et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1?/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat Commun. 2016;7:12723 pubmed publisher |
- western blot; human; 1:1000
| Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher |
- western blot; human; fig 4a
| Ramakrishnan S, Ku S, Ciamporcero E, Miles K, Attwood K, Chintala S, et al. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma. BMC Cancer. 2016;16:617 pubmed publisher |
- western blot; human; fig 3
| Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed publisher |
- western blot; human; loading ...; fig 6
| Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, et al. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochim Biophys Acta. 2016;1862:2004-14 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 7b
| Merry C, McMahon S, Forrest M, Bartels C, Saiakhova A, Bartel C, et al. Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer. Oncotarget. 2016;7:53230-53244 pubmed publisher |
- western blot; mouse; loading ...; fig 3c
| Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5f
| Heckler M, Zeleke T, Divekar S, Fernandez A, Tiek D, Woodrick J, et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. Oncotarget. 2016;7:47201-47220 pubmed publisher |
- western blot; human; fig 6a
| Gao X, Lin S, Ren F, Li J, Chen J, Yao C, et al. Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia. Nat Commun. 2016;7:11960 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Park W, Kim H, Kang D, Ryu J, Choi K, Lee G, et al. Comparative expression patterns and diagnostic efficacies of SR splicing factors and HNRNPA1 in gastric and colorectal cancer. BMC Cancer. 2016;16:358 pubmed publisher |
- immunohistochemistry; fruit fly ; 1:200; fig s1
| Upadhyay M, Martino Cortez Y, Wong Deyrup S, Tavares L, Schowalter S, Flora P, et al. Transposon Dysregulation Modulates dWnt4 Signaling to Control Germline Stem Cell Differentiation in Drosophila. PLoS Genet. 2016;12:e1005918 pubmed publisher |
- western blot; mouse; fig 2
- western blot; human; fig 1
| Ladurner R, Kreidl E, Ivanov M, Ekker H, Idarraga Amado M, Busslinger G, et al. Sororin actively maintains sister chromatid cohesion. EMBO J. 2016;35:635-53 pubmed publisher |
- western blot; human; fig 6d
| Chuang T, Lee K, Lou Y, Lu C, Tarn W. A Point Mutation in the Exon Junction Complex Factor Y14 Disrupts Its Function in mRNA Cap Binding and Translation Enhancement. J Biol Chem. 2016;291:8565-74 pubmed publisher |
- western blot; Xenopus laevis; fig 4
| Aparicio T, Baer R, Gottesman M, Gautier J. MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts. J Cell Biol. 2016;212:399-408 pubmed publisher |
- chromatin immunoprecipitation; mouse; loading ...
| Liao K, Guo M, Niu F, Yang L, Callen S, Buch S. Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis. J Neuroinflammation. 2016;13:33 pubmed publisher |
- western blot; human; loading ...; fig s3t
| Taniue K, Kurimoto A, Sugimasa H, Nasu E, Takeda Y, Iwasaki K, et al. Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1. Proc Natl Acad Sci U S A. 2016;113:1273-8 pubmed publisher |
- western blot; mouse; 1:2000; fig 2
| Benitz S, Regel I, Reinhard T, Popp A, Schäffer I, Raulefs S, et al. Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells. Oncotarget. 2016;7:11424-33 pubmed publisher |
- western blot; human; fig 6a
| Matsuda S, Adachi J, Ihara M, Tanuma N, Shima H, Kakizuka A, et al. Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor. Nucleic Acids Res. 2016;44:636-47 pubmed publisher |
| Zhai D, Cui C, Xie L, Cai L, Yu J. Sterol regulatory element-binding protein 1 cooperates with c-Myc to promote epithelial-mesenchymal transition in colorectal cancer. Oncol Lett. 2018;15:5959-5965 pubmed publisher |
| Tan S, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, et al. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability. Cell. 2017;169:1105-1118.e15 pubmed publisher |
| Granata C, Oliveira R, Little J, Renner K, Bishop D. Sprint-interval but not continuous exercise increases PGC-1α protein content and p53 phosphorylation in nuclear fractions of human skeletal muscle. Sci Rep. 2017;7:44227 pubmed publisher |
| Cho H, Um J, Lee J, Kim W, Kang W, Kim S, et al. ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes. Sci Rep. 2017;7:44186 pubmed publisher |
| Mason J, Wei X, Fletcher G, Kiarash R, Brokx R, Hodgson R, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017;114:3127-3132 pubmed publisher |
| Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, et al. Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Cell Death Dis. 2017;8:e2570 pubmed publisher |
| Pike T, Brownlow N, Kjaer S, Carlton J, Parker P. PKC? switches Aurora B specificity to exit the abscission checkpoint. Nat Commun. 2016;7:13853 pubmed publisher |
| Wang X, Sehgal L, Jain N, Khashab T, Mathur R, Samaniego F. LncRNA MALAT1 promotes development of mantle cell lymphoma by associating with EZH2. J Transl Med. 2016;14:346 pubmed publisher |
| Sokolova M, Turunen M, Mortusewicz O, Kivioja T, Herr P, Vähärautio A, et al. Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. Cell Cycle. 2017;16:189-199 pubmed publisher |
| Coster A, Thorne C, Wu L, Altschuler S. Examining Crosstalk among Transforming Growth Factor β, Bone Morphogenetic Protein, and Wnt Pathways. J Biol Chem. 2017;292:244-250 pubmed publisher |
| Sufit A, Lee Sherick A, DeRyckere D, Rupji M, Dwivedi B, Varella Garcia M, et al. MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme. PLoS ONE. 2016;11:e0165107 pubmed publisher |
| Kanwal R, Datt M, Liu X, Gupta S. Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases. PLoS ONE. 2016;11:e0162956 pubmed publisher |
| Dang F, Sun X, Ma X, Wu R, Zhang D, Chen Y, et al. Insulin post-transcriptionally modulates Bmal1 protein to affect the hepatic circadian clock. Nat Commun. 2016;7:12696 pubmed publisher |
| Liang K, Paredes R, Carmody R, Eyers P, Meyer S, McCarthy T, et al. Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C. Int J Mol Sci. 2016;17: pubmed publisher |
| Navarro Costa P, McCarthy A, Prudêncio P, Greer C, Guilgur L, Becker J, et al. Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat Commun. 2016;7:12331 pubmed publisher |
| Ding X, Ray Chaudhuri A, Callen E, Pang Y, Biswas K, Klarmann K, et al. Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies. Nat Commun. 2016;7:12425 pubmed publisher |
| Liu Y, Wang S, Long Y, Chen S, Li Y, Zhang J. KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway. Oncotarget. 2016;7:53153-53164 pubmed publisher |
| Ito S, Asakura M, Liao Y, Min K, Takahashi A, Shindo K, et al. Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy. J Am Heart Assoc. 2016;5: pubmed publisher |
| Hallenborg P, Siersbæk M, Barrio Hernandez I, Nielsen R, Kristiansen K, Mandrup S, et al. MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3. Cell Death Dis. 2016;7:e2289 pubmed publisher |
| Kaliszczak M, Trousil S, Ali T, Aboagye E. AKT activation controls cell survival in response to HDAC6 inhibition. Cell Death Dis. 2016;7:e2286 pubmed publisher |
| Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher |
| Ruiz Andrés O, Sanchez Nino M, Cannata Ortiz P, Ruiz Ortega M, Egido J, Ortiz A, et al. Histone lysine crotonylation during acute kidney injury in mice. Dis Model Mech. 2016;9:633-45 pubmed publisher |
| Kim C, Choi J, Joo S, Bae E, Ma S, Lee J, et al. Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. PLoS ONE. 2016;11:e0152591 pubmed publisher |
| Liu Y, Zhang D, Ping J, Li S, Chen Z, Ma J. Innovation of a Regulatory Mechanism Modulating Semi-determinate Stem Growth through Artificial Selection in Soybean. PLoS Genet. 2016;12:e1005818 pubmed publisher |
| Zheng F, Yue C, Li G, He B, Cheng W, Wang X, et al. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nat Commun. 2016;7:10180 pubmed publisher |
| Urahama T, Harada A, Maehara K, Horikoshi N, Sato K, Sato Y, et al. Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin. 2016;9:2 pubmed publisher |
| Salinas E, Byrum S, Moreland L, Mackintosh S, Tackett A, Forrest J. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016;90:1397-413 pubmed publisher |
