product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Histone H3 (Ser10) Antibody
catalog :
9701S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, chicken, zebrafish , fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 39
Published Application/Species/DilutionReference
  • immunocytochemistry; human; 1:50; fig 5
Huang C, Lee C, Yang S, Chien C, Huang C, Yang R, et al. Upregulation of the growth arrest-specific-2 in recurrent colorectal cancers, and its susceptibility to chemotherapy in a model cell system. Biochim Biophys Acta. 2016;1862:1345-53 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 5
Badal S, Wang Y, Long J, Corcoran D, CHANG B, Truong L, et al. miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. Nat Commun. 2016;7:12076 pubmed publisher
  • western blot; human; fig 6
  • western blot; mouse; fig 4
Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong R, Miller K, et al. Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov. 2016;6:188-201 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Hobbs R, Batazzi A, Han M, Coulombe P. Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo. Oncogene. 2016;: pubmed publisher
  • immunocytochemistry; mouse; fig 5
He D, Xiang J, Li B, Liu H. The dynamic behavior of Ect2 in response to DNA damage. Sci Rep. 2016;6:24504 pubmed publisher
  • western blot; human; 1:300; fig 1
Engel K, Rudelius M, Slawska J, Jacobs L, Ahangarian Abhari B, Altmann B, et al. USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma. EMBO Mol Med. 2016;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 2
Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed publisher
  • immunohistochemistry; mouse; fig 3 - figure supplement 1
Leggere J, Saito Y, Darnell R, Tessier-Lavigne M, Junge H, Chen Z. NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. elife. 2016;5: pubmed publisher
  • western blot; human; fig 4
Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3
Parchem R, Moore N, Fish J, Parchem J, Braga T, Shenoy A, et al. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015;12:760-73 pubmed publisher
  • immunocytochemistry; human; 1:500
Martinez R, Blasina A, Hallin J, Hu W, Rymer I, Fan J, et al. Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility. PLoS ONE. 2015;10:e0138616 pubmed publisher
  • western blot; mouse
Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  • immunohistochemistry; human; fig 7
Eriksson P, Aine M, Veerla S, Liedberg F, Sjödahl G, Hoglund M. Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems. BMC Med Genomics. 2015;8:25 pubmed publisher
  • immunohistochemistry - paraffin section; zebrafish; 1:50
Ju B, Chen W, Orr B, Spitsbergen J, Jia S, Eden C, et al. Oncogenic KRAS promotes malignant brain tumors in zebrafish. Mol Cancer. 2015;14:18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, et al. Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015;5:12982 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Chow H, Dong B, Duron S, Campbell D, Ong C, Hoeflich K, et al. Group I Paks as therapeutic targets in NF2-deficient meningioma. Oncotarget. 2015;6:1981-94 pubmed
  • immunohistochemistry; mouse; 1:200
  • immunohistochemistry; rat; 1:200
Walker K, Ikeda Y, Zabbarova I, Schaefer C, Bushnell D, de Groat W, et al. Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2015;308:F888-98 pubmed publisher
  • western blot; human; fig 6e
Guo Y, Feng W, Sy S, Huen M. ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response. J Biol Chem. 2015;290:27545-56 pubmed publisher
  • western blot; human; 1:5000
Ortega-Atienza S, Green S, Zhitkovich A. Proteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde. Toxicol Appl Pharmacol. 2015;286:135-41 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Hotchkiss A, Feridooni T, Baguma-Nibasheka M, McNeil K, Chinni S, Pasumarthi K. Atrial natriuretic peptide inhibits cell cycle activity of embryonic cardiac progenitor cells via its NPRA receptor signaling axis. Am J Physiol Cell Physiol. 2015;308:C557-69 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Garriock R, Mikawa T, Yamaguchi T. Isolation and culture of mouse proepicardium using serum-free conditions. Methods. 2014;66:365-9 pubmed publisher
  • immunohistochemistry; fruit fly; 1:100
Cordero J, Ridgway R, Valeri N, Nixon C, Frame M, Muller W, et al. c-Src drives intestinal regeneration and transformation. EMBO J. 2014;33:1474-91 pubmed publisher
  • western blot; human; 1:1000; fig 4d
Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Hilliard S, Yao X, El-Dahr S. Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014;387:1-14 pubmed publisher
  • western blot; human; fig 1c
Gallego-Paez L, Tanaka H, Bando M, Takahashi M, Nozaki N, Nakato R, et al. Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells. Mol Biol Cell. 2014;25:302-17 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Kim C, Pasparakis M. Epidermal p65/NF-κB signalling is essential for skin carcinogenesis. EMBO Mol Med. 2014;6:970-83 pubmed publisher
  • western blot; human; fig s2
Loukil A, Zonca M, Rebouissou C, Baldin V, Coux O, Biard-Piechaczyk M, et al. High-resolution live-cell imaging reveals novel cyclin A2 degradation foci involving autophagy. J Cell Sci. 2014;127:2145-50 pubmed publisher
  • immunocytochemistry; mouse; 1:500
Mäkelä J, Toppari J, Rivero-Muller A, Ventelä S. Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS ONE. 2014;9:e90088 pubmed publisher
  • western blot; human
Li A, Morton J, Ma Y, Karim S, Zhou Y, Faller W, et al. Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes. Gastroenterology. 2014;146:1386-96.e1-17 pubmed publisher
  • flow cytometry; chicken
Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Kim B, Zaveri H, Shchelochkov O, Yu Z, Hernandez-Garcia A, Seymour M, et al. An allelic series of mice reveals a role for RERE in the development of multiple organs affected in chromosome 1p36 deletions. PLoS ONE. 2013;8:e57460 pubmed publisher
  • western blot; human; 1:500
Boshnjaku V, Shim K, Tsurubuchi T, Ichi S, Szany E, Xi G, et al. Nuclear localization of folate receptor alpha: a new role as a transcription factor. Sci Rep. 2012;2:980 pubmed publisher
  • western blot; mouse
Leng J, Butcher B, Egan C, Abi Abdallah D, Denkers E. Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. J Immunol. 2009;182:489-97 pubmed
Weng R, Cohen S. Control of Drosophila Type I and Type II central brain neuroblast proliferation by bantam microRNA. Development. 2015;142:3713-20 pubmed publisher
Deng X, von Keudell G, Suzuki T, Dohmae N, Nakakido M, Piao L, et al. PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP. Oncotarget. 2015;6:35173-82 pubmed publisher
Vondálová Blanárová O, Jelinkova I, Hyrslova Vaculova A, Sova P, Hofmanova J, Kozubik A. Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells. Cell Prolif. 2013;46:665-76 pubmed publisher
Cheung C, Lin W, Hsu J, Hour T, Yeh T, Ko S, et al. BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells. PLoS ONE. 2011;6:e23485 pubmed publisher
Keil K, Mehta V, Branam A, Abler L, Buresh-Stiemke R, Joshi P, et al. Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development. Endocrinology. 2012;153:6091-103 pubmed publisher
Song N, Liu J, An S, Nishino T, Hishikawa Y, Koji T. Immunohistochemical Analysis of Histone H3 Modifications in Germ Cells during Mouse Spermatogenesis. Acta Histochem Cytochem. 2011;44:183-90 pubmed
product information
SKU :
9701S
Product-Name :
Phospho-Histone H3 (Ser10) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, C, Dm, Z, Sc, (X)
Applications :
Flow cytometry
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
17
Host :
Rabbit
Target :
H3 (Ser11) phosphate
Primary-Protein :
H3
Alt-Names :
H3 histone family, member A,H3/A,H31,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,histone 1, H3a,histone cluster 1, H3a
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.