product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Integrin β1 (D2E5) Rabbit mAb
catalog :
9699
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2E5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 9c
Li K, Wu R, Zhou M, Tong H, Luo K. Desmosomal proteins of DSC2 and PKP1 promote cancer cells survival and metastasis by increasing cluster formation in circulatory system. Sci Adv. 2021;7:eabg7265 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2b
Saito K, Mitsui A, Sumardika I, Yokoyama Y, Sakaguchi M, Kondo E. PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1. Int J Oncol. 2021;58: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2e
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed publisher
  • immunohistochemistry; human; loading ...; fig 4d, 3b
Iqbal N, Jascur T, Harrison S, Edwards A, Smith L, Choi E, et al. Prune belly syndrome in surviving males can be caused by Hemizygous missense mutations in the X-linked Filamin A gene. BMC Med Genet. 2020;21:38 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2d
Wang M, Hinton J, Gard J, Garcia J, Knudsen B, Nagle R, et al. Integrin α6β4E variant is associated with actin and CD9 structures and modifies the biophysical properties of cell-cell and cell-extracellular matrix interactions. Mol Biol Cell. 2019;30:838-850 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
  • western blot; human; 1:1000; fig s5b
Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, et al. Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. Arterioscler Thromb Vasc Biol. 2017;37:1115-1126 pubmed publisher
  • western blot; human; loading ...; fig 3h
Merhi A, Delree P, Marini A. The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling. Sci Rep. 2017;7:44602 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig ev3b
Fallahi Sichani M, Becker V, Izar B, Baker G, Lin J, Boswell S, et al. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Mol Syst Biol. 2017;13:905 pubmed publisher
  • western blot; human; loading ...; fig 1d
Parag Sharma K, Leyme A, DiGiacomo V, Marivin A, Broselid S, Garcia Marcos M. Membrane Recruitment of the Non-receptor Protein GIV/Girdin (G?-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling. J Biol Chem. 2016;291:27098-27111 pubmed publisher
  • western blot; human; 1:200; fig 4
Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 4
Wang B, Qi T, Chen S, Ye L, Huang Z, Li H. RFX1 maintains testis cord integrity by regulating the expression of Itga6 in male mouse embryos. Mol Reprod Dev. 2016;83:606-14 pubmed publisher
  • western blot; human; 1:1000; fig 6
Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, et al. Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci. 2016;107:84-94 pubmed publisher
  • western blot; human; fig 4
Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
  • western blot; human; fig s6
Scott D, Tolbert C, Graham D, Wittchen E, Bear J, Burridge K. N-glycosylation controls the function of junctional adhesion molecule-A. Mol Biol Cell. 2015;26:3205-14 pubmed publisher
Cai Y, Cui W, Chen W, Wei P, Chi Y, Zhang P, et al. The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms. Cancer Cell Int. 2013;13:57 pubmed publisher
product information
SKU :
9699S
Product-Name :
Integrin β1 (D2E5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
115, 135
Host :
Rabbit
Target :
Integrin Beta1
Primary-Protein :
ITGB1
Alt-Names :
CD29,FNRB,Fibronectin receptor subunit beta,GPIIA,ITB1,ITGB1,Integrin beta-1,MDF2,MSK12,VLA-4 subunit beta,VLA-BETA,VLAB,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.