| Published Application/Species/Sample/Dilution | Reference |
|---|
- ChIP-Seq; human; loading ...; fig 2i, 6e
| Goel S, Bhatia V, Kundu S, Biswas T, Carskadon S, Gupta N, et al. Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progression. Nat Commun. 2021;12:5325 pubmed publisher |
- chromatin immunoprecipitation; mouse; 1:50; fig 4h
- western blot; mouse; 1:1000; fig 4i
| Xu P, Xiong W, Lin Y, Fan L, Pan H, Li Y. Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression. Cell Death Dis. 2021;12:779 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1c
| Martínez Gutiérrez A, Fernández Duran I, Marazuela Duque A, Simonet N, Yousef I, Martínez Rovira I, et al. Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1. Aging (Albany NY). 2021;13:12308-12333 pubmed publisher |
- chromatin immunoprecipitation; human; 1:50; loading ...; fig 3d
| Long Z, Deng L, Li C, He Q, He Y, Hu X, et al. Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer. Cell Death Dis. 2021;12:46 pubmed publisher |
- western blot; human; 1:1000; loading ...
| Fang M, Zhang M, Wang Y, Wei F, Wu J, Mou X, et al. Long Noncoding RNA AFAP1-AS1 Is a Critical Regulator of Nasopharyngeal Carcinoma Tumorigenicity. Front Oncol. 2020;10:601055 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3a
| Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher |
- western blot; rat; ; loading ...; fig 6s1a
- western blot; mouse; ; loading ...; fig 6s1b, 6s1c, 6s1d
| Currais A, Huang L, Goldberg J, Petrascheck M, Ates G, Pinto Duarte A, et al. Elevating acetyl-CoA levels reduces aspects of brain aging. elife. 2019;8: pubmed publisher |
- immunoprecipitation; mouse; 1:25; loading ...; fig 13g
- western blot; mouse; 1:1000; fig s13c
| Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 1f
| Liszczak G, Diehl K, Dann G, Muir T. Acetylation blocks DNA damage-induced chromatin ADP-ribosylation. Nat Chem Biol. 2018;14:837-840 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1a
| Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher |
- western blot; human; loading ...; fig 7a
| Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 9a
| Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher |
- western blot; mouse; fig 4c
| Wu N, Jia D, Bates B, Basom R, Eberhart C, MacPherson D. A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence. J Clin Invest. 2017;127:888-898 pubmed publisher |
- western blot; human; loading ...; fig 2b
| Mondello P, Derenzini E, Asgari Z, Philip J, Brea E, SESHAN V, et al. Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma. Oncotarget. 2017;8:14017-14028 pubmed publisher |
- other; human; 1:2500; loading ...; fig s9
| He Y, Selvaraju S, Curtin M, Jakob C, Zhu H, Comess K, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017;13:389-395 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 5b
| Endorf E, Qing H, Aono J, Terami N, Doyon G, Hyzny E, et al. Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. Arterioscler Thromb Vasc Biol. 2017;37:301-311 pubmed publisher |
- western blot; brewer's yeast; loading ...; fig s1a
| Desfossés Baron K, Hammond Martel I, Simoneau A, Sellam A, Roberts S, Wurtele H. Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae. Sci Rep. 2016;6:36013 pubmed publisher |
- chromatin immunoprecipitation; human; loading ...; fig 5b
- western blot; human; loading ...; fig 4d
| Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, et al. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. 2016;7:56338-56354 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Ono H, Basson M, Ito H. P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer. Oncotarget. 2016;7:51301-51310 pubmed publisher |
- chromatin immunoprecipitation; human; fig 7
- western blot; human; fig 7
| Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 11a
| Perez R, Shen H, Duan L, Kim R, Kim T, Park N, et al. Modeling the Etiology of p53-mutated Cancer Cells. J Biol Chem. 2016;291:10131-47 pubmed publisher |
- western blot; human; fig 5c
| Heo J, Kim W, Choi K, Bae S, Jeong J, Kim K. XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. Oncotarget. 2016;7:5118-30 pubmed publisher |
- western blot; human; fig 1
| Terranova Barberio M, Roca M, Zotti A, Leone A, Bruzzese F, Vitagliano C, et al. Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression. Oncotarget. 2016;7:7715-31 pubmed publisher |
| Namachivayam K, Mohankumar K, Arbach D, Jagadeeswaran R, Jain S, Natarajan V, et al. All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2. PLoS ONE. 2015;10:e0134003 pubmed publisher |
- western blot; human; fig 5
| Montgomery D, Sorum A, Guasch L, Nicklaus M, Meier J. Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors. Chem Biol. 2015;22:1030-1039 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed publisher |
- western blot; human; fig 7
| Bardhan K, Paschall A, Yang D, Chen M, Simon P, Bhutia Y, et al. IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer. Cancer Immunol Res. 2015;3:795-805 pubmed publisher |
- chromatin immunoprecipitation; human; fig 5
| Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, et al. Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. elife. 2014;3: pubmed publisher |
- chromatin immunoprecipitation; human
| Ray S, Li H, Metzger E, Schüle R, Leiter A. CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells. Mol Cell Biol. 2014;34:2308-17 pubmed publisher |
| Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher |
- chromatin immunoprecipitation; human
| Feng Y, Wu H, Xu Y, Zhang Z, Liu T, Lin X, et al. Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-? signaling. J Biol Chem. 2014;289:2072-83 pubmed publisher |
| Lauffer B, Mintzer R, Fong R, Mukund S, Tam C, Zilberleyb I, et al. Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability. J Biol Chem. 2013;288:26926-43 pubmed publisher |
| Zhao J, Yue W, Zhu M, Du M. AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5. J Biol Chem. 2011;286:16426-34 pubmed publisher |
| Kumar M, Molkentine D, Molkentine J, Bridges K, Xie T, Yang L, et al. Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function. Nat Commun. 2021;12:6340 pubmed publisher |
| Safari M, Litman T, Robey R, Aguilera A, Chakraborty A, Reinhold W, et al. R-Loop-Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin. Mol Cancer Res. 2021;19:1361-1374 pubmed publisher |
| Hobson C, Kern M, O Brien E, Stephens A, Falvo M, Superfine R. Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics. Mol Biol Cell. 2020;31:1788-1801 pubmed publisher |
| Diaz Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al. In vitro characterization of the human segmentation clock. Nature. 2020;580:113-118 pubmed publisher |
| Lombó M, Getino Álvarez L, Depince A, Labbe C, Herraez M. Embryonic Exposure to Bisphenol A Impairs Primordial Germ Cell Migration without Jeopardizing Male Breeding Capacity. Biomolecules. 2019;9: pubmed publisher |
| Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 2019;177:622-638.e22 pubmed publisher |
| Nugent B, O Donnell C, Epperson C, Bale T. Placental H3K27me3 establishes female resilience to prenatal insults. Nat Commun. 2018;9:2555 pubmed publisher |
| Ali D, Chalisserry E, Manikandan M, Hamam R, Alfayez M, Kassem M, et al. Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity. Stem Cells Int. 2018;2018:2379546 pubmed publisher |
| Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, et al. Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer. Nat Genet. 2018;50:219-228 pubmed publisher |
| Epanchintsev A, Costanzo F, Rauschendorf M, Caputo M, Ye T, Donnio L, et al. Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation. Mol Cell. 2017;68:1054-1066.e6 pubmed publisher |
| Stephens A, Liu P, Banigan E, Almassalha L, Backman V, Adam S, et al. Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins. Mol Biol Cell. 2018;29:220-233 pubmed publisher |
| Lv D, Jia F, Hou Y, Sang Y, Alvarez A, Zhang W, et al. Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding. Cancer Res. 2017;77:6190-6201 pubmed publisher |
| Zheng L, Kelly C, Battista K, Schaefer R, Lanis J, Alexeev E, et al. Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2. J Immunol. 2017;199:2976-2984 pubmed publisher |
| Hashwah H, Schmid C, Kasser S, Bertram K, Stelling A, Manz M, et al. Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth. Proc Natl Acad Sci U S A. 2017;114:9701-9706 pubmed publisher |
| Huang C, Chang P, Kuo W, Chen C, Jeng Y, Chang K, et al. Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate. Nat Commun. 2017;8:14706 pubmed publisher |
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| Rajarajacholan U, Thalappilly S, Riabowol K. ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization. Nucleic Acids Res. 2017;45:1776-1792 pubmed publisher |
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| Zhao G, Xu L, Pan H, Lin Q, Huang M, Cai J, et al. The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling. Oncotarget. 2015;6:38952-66 pubmed publisher |
| Finegersh A, Ferguson C, Maxwell S, Mazariegos D, Farrell D, Homanics G. Repeated vapor ethanol exposure induces transient histone modifications in the brain that are modified by genotype and brain region. Front Mol Neurosci. 2015;8:39 pubmed publisher |
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