Phospho-Tau (Ser396) (PHF13) Mouse mAb | Cell Signaling Technology 9632 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-Tau (Ser396) (PHF13) Mouse mAb

catalog :

9632

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

PHF13

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - free floating section

more info or order :

Cell Signaling Technology product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig e1a	Faraco G, Hochrainer K, Segarra S, Schaeffer S, Santisteban M, Menon A, et al. Dietary salt promotes cognitive impairment through tau phosphorylation. Nature. 2019;: pubmed publisher
western blot; mouse; 1:200; loading ...; fig 3a	di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed publisher
immunohistochemistry - free floating section; mouse; loading ...; fig s5d western blot; mouse; loading ...; fig s5g	Martorell A, Paulson A, Suk H, Abdurrob F, Drummond G, Guan W, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. 2019;177:256-271.e22 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 1f	Merezhko M, Brunello C, Yan X, Vihinen H, Jokitalo E, Uronen R, et al. Secretion of Tau via an Unconventional Non-vesicular Mechanism. Cell Rep. 2018;25:2027-2035.e4 pubmed publisher
western blot; mouse; 1:200; loading ...; fig 3a	di Meco A, Li J, Blass B, Abou Gharbia M, Lauretti E, PraticÃ² D. 12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice. Biol Psychiatry. 2017;81:92-100 pubmed publisher
western blot; human; 1:4000; loading ...; fig 4a	Sun W, Lee S, Huang X, Liu S, Inayathullah M, Kim K, et al. Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment. Sci Rep. 2016;6:34784 pubmed publisher
western blot; human; fig 3	Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed publisher
western blot; mouse; 1:1000; fig 3	Lee I, Jung K, Kim I, Lee H, Kim M, Yun S, et al. Human neural stem cells alleviate Alzheimer-like pathology in a mouse model. Mol Neurodegener. 2015;10:38 pubmed publisher
western blot; mouse; fig 1	Lauretti E, PraticÃ² D. Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase. Aging Cell. 2015;14:1067-74 pubmed publisher
western blot; mouse; 1:200	Lauretti E, di Meco A, Chu J, PraticÃ² D. Modulation of AD neuropathology and memory impairments by the isoprostane F2Î± is mediated by the thromboxane receptor. Neurobiol Aging. 2015;36:812-20 pubmed publisher
	Lauretti E, Nenov M, Dincer O, Iuliano L, Pratico D. Extra virgin olive oil improves synaptic activity, short-term plasticity, memory, and neuropathology in a tauopathy model. Aging Cell. 2020;19:e13076 pubmed publisher
	Ko H, Chiou S, Wong Y, Wang Y, Lai Y, Chou C, et al. GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease. J Clin Med. 2019;8: pubmed publisher
	Neddens J, Temmel M, Flunkert S, Kerschbaumer B, Hoeller C, Loeffler T, et al. Phosphorylation of different tau sites during progression of Alzheimer's disease. Acta Neuropathol Commun. 2018;6:52 pubmed publisher
	di Meco A, Li J, Barrero C, Merali S, Pratico D. Elevated levels of brain homocysteine directly modulate the pathological phenotype of a mouse model of tauopathy. Mol Psychiatry. 2018;: pubmed publisher
	Jang E, Sim A, Im S, Hur E. Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons. Neural Plast. 2016;2016:5056418 pubmed
	Magistri M, Velmeshev D, Makhmutova M, Patel P, Sartor G, Volmar C, et al. The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. Curr Alzheimer Res. 2016;13:985-95 pubmed
	Zigdon H, Savidor A, Levin Y, Meshcheriakova A, Schiffmann R, Futerman A. Identification of a biomarker in cerebrospinal fluid for neuronopathic forms of Gaucher disease. PLoS ONE. 2015;10:e0120194 pubmed publisher
	Shimokawa N, Koibuchi N. Downregulation of receptor tyrosine kinases through ubiquitination: analysis by immunodetection. Methods Mol Biol. 2015;1233:121-33 pubmed publisher
	Å polcovÃ¡ A, MikulÃ¡Å¡kovÃ¡ B, KrÅ¡kovÃ¡ K, GajdoÅ¡echovÃ¡ L, ZÃ³rad Å, Olszanecki R, et al. Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats. BMC Neurosci. 2014;15:111 pubmed publisher
	Li J, Chu J, Barrero C, Merali S, Pratico D. Homocysteine exacerbates ?-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles. Ann Neurol. 2014;75:851-63 pubmed publisher
	Li H, Wu X, Wu Q, Gong D, Shi M, Guan L, et al. Green tea polyphenols protect against okadaic acid-induced acute learning and memory impairments in rats. Nutrition. 2014;30:337-42 pubmed publisher
	Yi R, Chen B, Zhao J, Zhan X, Zhang L, Liu X, et al. Krüppel-like factor 8 ameliorates Alzheimer's disease by activating ?-catenin. J Mol Neurosci. 2014;52:231-41 pubmed publisher
	Sierksma A, Van den Hove D, Pfau F, Philippens M, Bruno O, Fedele E, et al. Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D. Neuropharmacology. 2014;77:120-30 pubmed publisher
	Nykänen N, Kysenius K, Sakha P, Tammela P, Huttunen H. ?-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation. J Biol Chem. 2012;287:6743-52 pubmed publisher

product information

SKU :

9632S

Product-Name :

Phospho-Tau (Ser396) (PHF13) Mouse mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

M, R, (H)

Applications :

Western blot

Product-Category :

Neuroscience

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

50-80

Host :

Mouse

Target :

tau (Ser396) phosphate

Primary-Protein :

tau iso8

Alt-Names :

DDPAC,FLJ31424,FTDP-17,G protein beta1/gamma2 subunit-interacting factor 1,MAPT,MAPTL,MGC138549,MSTD,MTBT1,MTBT2,Microtubule-associated protein tau,Neurofibrillary tangle protein,PHF-tau,PPND,Paired helical filament-tau,TAU

more info or order :

Cell Signaling Technology product webpage