product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-(Ser/Thr) PKA Substrate Antibody
catalog :
9621
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 7b
Mao L, Kitani A, Similuk M, Oler A, Albenberg L, Kelsen J, et al. Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease. J Clin Invest. 2018;128:1793-1806 pubmed publisher
  • western blot; human; loading ...; fig 1c, 1d, 1e
Kline C, Ralff M, Lulla A, Wagner J, Abbosh P, Dicker D, et al. Role of Dopamine Receptors in the Anticancer Activity of ONC201. Neoplasia. 2018;20:80-91 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5c
Xiao N, Yang L, Yang Y, Liu L, Li J, Liu B, et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol. 2017;8:43 pubmed publisher
  • western blot; mouse; 1:1000; fig 4c
Cederquist C, Lentucci C, Martinez Calejman C, Hayashi V, Orofino J, GUERTIN D, et al. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017;6:125-137 pubmed publisher
  • western blot; mouse; loading ...; fig 6d
Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher
  • western blot; mouse; fig 3
Zhao W, Li A, Feng X, Hou T, Liu K, Liu B, et al. Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cell Signal. 2016;28:1401-11 pubmed publisher
  • western blot; human; fig 1
Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed
  • western blot; rat; fig 2
Asalla S, Girada S, Kuna R, Chowdhury D, Kandagatla B, Oruganti S, et al. Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells. Sci Rep. 2016;6:27513 pubmed publisher
  • western blot; human; 1:1000; fig 3j
Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed publisher
  • immunoprecipitation; human; fig 2
Mahesh P, Retnakumar R, Mundayoor S. Downregulation of vimentin in macrophages infected with live Mycobacterium tuberculosis is mediated by Reactive Oxygen Species. Sci Rep. 2016;6:21526 pubmed publisher
  • immunohistochemistry; chicken; 1:50; fig 4
Xie Q, McGreal R, Harris R, Gao C, Liu W, Reneker L, et al. Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling. J Biol Chem. 2016;291:3947-58 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Messaoudi S, He Y, Gutsol A, Wight A, Hébert R, Vilmundarson R, et al. Endothelial Gata5 transcription factor regulates blood pressure. Nat Commun. 2015;6:8835 pubmed publisher
  • western blot; mouse; loading ...; fig 3d
Li M, Quan C, Toth R, Campbell D, MacKintosh C, Wang H, et al. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders. J Biol Chem. 2015;290:30030-41 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  • western blot; human
Wnorowski A, Sadowska M, Paul R, Singh N, Boguszewska Czubara A, Jimenez L, et al. Activation of β2-adrenergic receptor by (R,R')-4'-methoxy-1-naphthylfenoterol inhibits proliferation and motility of melanoma cells. Cell Signal. 2015;27:997-1007 pubmed publisher
  • western blot; human; fig  3
Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
  • immunocytochemistry; mouse
Mottillo E, Paul G, Moore H, Granneman J. Use of fluorescence microscopy to probe intracellular lipolysis. Methods Enzymol. 2014;538:263-78 pubmed publisher
  • western blot; mouse
Zhu H, Guariglia S, Li W, Brancho D, Wang Z, Scherer P, et al. Role of extracellular signal-regulated kinase 5 in adipocyte signaling. J Biol Chem. 2014;289:6311-22 pubmed publisher
  • western blot; human
Neukamm S, Ott J, Dammeier S, Lehmann R, Haring H, Schleicher E, et al. Phosphorylation of serine 1137/1138 of mouse insulin receptor substrate (IRS) 2 regulates cAMP-dependent binding to 14-3-3 proteins and IRS2 protein degradation. J Biol Chem. 2013;288:16403-15 pubmed publisher
Li K, Zhang J, Yu J, Liu B, Guo Y, Deng J, et al. MicroRNA-214 suppresses gluconeogenesis by targeting activating transcriptional factor 4. J Biol Chem. 2015;290:8185-95 pubmed publisher
Yamazaki F, Kim H, Lau P, Hwang C, Iuvone P, Klein D, et al. pY RNA1-s2: a highly retina-enriched small RNA that selectively binds to Matrin 3 (Matr3). PLoS ONE. 2014;9:e88217 pubmed publisher
product information
SKU :
9621S
Product-Name :
Phospho-(Ser/Thr) PKA Substrate Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
All
Applications :
ELISA Peptide
Product-Category :
Motif Antibodies
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
Host :
Rabbit
Target :
RRXT-P
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.