product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Akt Substrate (RXXS*/T*) (110B7E) Rabbit mAb
catalog :
9614L
quantity :
300 ul
price :
658 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
, human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 9
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000
Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  • western blot; human; 1:1000; fig 2
Tollenaere M, Villumsen B, Blasius M, Nielsen J, Wagner S, Bartek J, et al. p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1. Nat Commun. 2015;6:10075 pubmed publisher
  • western blot; mouse; fig 3
Kleinert M, Sylow L, Fazakerley D, Krycer J, Thomas K, Oxbøll A, et al. Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Mol Metab. 2014;3:630-41 pubmed publisher
  • western blot; human; fig 1b
Dai X, North B, Inuzuka H. Negative regulation of DAB2IP by Akt and SCFFbw7 pathways. Oncotarget. 2014;5:3307-15 pubmed
  • western blot; human
Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed publisher
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed publisher
Hamaguchi T, Nakamuta S, Funahashi Y, Takano T, Nishioka T, Shohag M, et al. In vivo screening for substrates of protein kinase A using a combination of proteomic approaches and pharmacological modulation of kinase activity. Cell Struct Funct. 2015;40:1-12 pubmed publisher
Koumanov F, Richardson J, Murrow B, Holman G. AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane. J Biol Chem. 2011;286:16574-82 pubmed publisher
Fonseca B, Alain T, Finestone L, Huang B, Rolfe M, Jiang T, et al. Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbo. J Biol Chem. 2011;286:27111-22 pubmed publisher
product information
SKU :
9614L
Product-Name :
Phospho-Akt Substrate (RXXS*/T*) (110B7E) Rabbit mAb
Size :
300 ul
Price-(USD) :
658 USD
Species-x-Reactivity :
All
Applications :
ELISA Peptide
Product-Category :
Motif Antibodies
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Akt-phosphate Substrate (Ser/Thr) phosphate
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.