product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-(Ser/Thr) Akt Substrate Antibody
catalog :
9611S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
fission yeast, human, mouse, cow
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 22
Published Application/Species/DilutionReference
  • western blot; fission yeast; fig 5
Ma N, Ma Y, Nakashima A, Kikkawa U, Furuyashiki T. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast. PLoS ONE. 2016;11:e0156239 pubmed publisher
  • western blot; human; fig 4
Patergnani S, Giorgi C, Maniero S, Missiroli S, Maniscalco P, Bononi I, et al. The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition. Oncotarget. 2015;6:23427-44 pubmed
  • western blot; mouse
Quan C, Xie B, Wang H, Chen S. PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. PLoS ONE. 2015;10:e0124491 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Maria Z, Campolo A, Lacombe V. Diabetes Alters the Expression and Translocation of the Insulin-Sensitive Glucose Transporters 4 and 8 in the Atria. PLoS ONE. 2015;10:e0146033 pubmed publisher
  • western blot; mouse
Liu X, Giguere V. Inactivation of RARβ inhibits Wnt1-induced mammary tumorigenesis by suppressing epithelial-mesenchymal transitions. Nucl Recept Signal. 2014;12:e004 pubmed publisher
  • western blot; human
Mortensen B, Friedrichsen M, Andersen N, Alibegovic A, Højbjerre L, Sonne M, et al. Physical inactivity affects skeletal muscle insulin signaling in a birth weight-dependent manner. J Diabetes Complications. 2014;28:71-8 pubmed publisher
  • western blot; human; 1:1000
Hellesøy M, Blois A, Tiron C, Mannelqvist M, Akslen L, Lorens J. Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis. Tissue Eng Part A. 2014;20:2590-603 pubmed publisher
  • western blot; cow; 1:1000
Ahmed N, Iu J, Brown C, Taylor D, Kandel R. Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction. Tissue Eng Part A. 2014;20:2224-33 pubmed publisher
  • western blot; mouse
Treebak J, Pehmøller C, Kristensen J, Kjøbsted R, Birk J, Schjerling P, et al. Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle. J Physiol. 2014;592:351-75 pubmed publisher
  • western blot; human
Liang H, Hussey S, Sanchez-Avila A, Tantiwong P, Musi N. Effect of lipopolysaccharide on inflammation and insulin action in human muscle. PLoS ONE. 2013;8:e63983 pubmed publisher
  • western blot; human
Liang H, Tantiwong P, Sriwijitkamol A, Shanmugasundaram K, Mohan S, Espinoza S, et al. Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects. J Physiol. 2013;591:2897-909 pubmed publisher
He H, Qiao X, Wu S. Carbamylated erythropoietin attenuates cardiomyopathy via PI3K/Akt activation in rats with diabetic cardiomyopathy. Exp Ther Med. 2013;6:567-573 pubmed
Bruss M, Arias E, Lienhard G, Cartee G. Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity. Diabetes. 2005;54:41-50 pubmed
Fonseca B, Alain T, Finestone L, Huang B, Rolfe M, Jiang T, et al. Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbo. J Biol Chem. 2011;286:27111-22 pubmed publisher
Srirangam A, Mitra R, Wang M, Gorski J, Badve S, Baldridge L, et al. Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer. Clin Cancer Res. 2006;12:1883-96 pubmed
Contreras X, Barboric M, Lenasi T, Peterlin B. HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription. PLoS Pathog. 2007;3:1459-69 pubmed
Højlund K, Glintborg D, Andersen N, Birk J, Treebak J, Frøsig C, et al. Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment. Diabetes. 2008;57:357-66 pubmed
Karlsson H, Ahlsén M, Zierath J, Wallberg-Henriksson H, Koistinen H. Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients. Diabetes. 2006;55:1283-8 pubmed
Wada S, Tanabe K, Yamazaki A, Niimi M, Uehara Y, Niimi K, et al. Phosphorylation of candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability. J Biol Chem. 2005;280:94-103 pubmed
Trinidad A, de la Puerta M, Fernández N, Bayon Y, Crespo M, Alonso A. Coupling of C3bi to IgG inhibits the tyrosine phosphorylation signaling cascade downstream Syk and reduces cytokine induction in monocytes. J Leukoc Biol. 2006;79:1073-82 pubmed
Zhao H, Shimohata T, Wang J, Sun G, Schaal D, Sapolsky R, et al. Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. J Neurosci. 2005;25:9794-806 pubmed
Nascimento E, Fodor M, van der Zon G, Jazet I, Meinders A, Voshol P, et al. Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats. Diabetes. 2006;55:3221-8 pubmed
product information
SKU :
9611S
Product-Name :
Phospho-(Ser/Thr) Akt Substrate Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
All
Applications :
ELISA Peptide
Product-Category :
Motif Antibodies
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
Host :
Rabbit
Target :
Akt-phosphate Substrate (Ser/Thr) phosphate
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.