product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
β-Catenin (6B3) Rabbit mAb
catalog :
9582
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
6B3
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig s8h
Wang W, Wang Y, Qu C, Wang S, Zhou J, Cao W, et al. The RNA genome of hepatitis E virus robustly triggers an antiviral interferon response. Hepatology. 2018;67:2096-2112 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 7e
  • western blot; mouse; 1:1000; loading ...; fig 7c
Olvedy M, Tisserand J, Luciani F, Boeckx B, Wouters J, Lopez S, et al. Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma. J Clin Invest. 2017;127:2310-2325 pubmed publisher
  • western blot; human; loading ...; fig 1b
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; loading ...; fig 6d, 6e
Xu D, Zhou P, Wang Y, Zhang Y, Zhang R, Zhang L, et al. miR-150 Suppresses the Proliferation and Tumorigenicity of Leukemia Stem Cells by Targeting the Nanog Signaling Pathway. Front Pharmacol. 2016;7:439 pubmed
  • western blot; human; fig 1a
Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed publisher
  • western blot; human; fig 2
Park S, Yoon S, Kim H, Kim K. 90K Glycoprotein Promotes Degradation of Mutant ?-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus. Neoplasia. 2016;18:618-625 pubmed publisher
  • western blot; human; 1:1000; fig 1
Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1g
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1g
Gerling M, Büller N, Kirn L, Joost S, Frings O, Englert B, et al. Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth. Nat Commun. 2016;7:12321 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:25; loading ...; fig 6a
  • immunocytochemistry; mouse; 1:25; fig 5a
Cantú A, Altshuler Keylin S, Laird D. Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling. J Cell Biol. 2016;214:215-29 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1b
Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, et al. Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit. Oncotarget. 2016;7:45414-45428 pubmed publisher
  • western blot; human; fig s1b
Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/?-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7:42513-42526 pubmed publisher
  • western blot; mouse; fig 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  • immunohistochemistry; human; 1:500; loading ...; fig 5d
Rafehi S, Ramos Valdes Y, Bertrand M, McGee J, Préfontaine M, Sugimoto A, et al. TGFβ signaling regulates epithelial-mesenchymal plasticity in ovarian cancer ascites-derived spheroids. Endocr Relat Cancer. 2016;23:147-59 pubmed publisher
  • western blot; rat; 1:1000; fig 3b
Zhang Y, Dai Q, Chen W, Jiang S, Chen S, Zhang Y, et al. Effects of acupuncture on cortical expression of Wnt3a, β-catenin and Sox2 in a rat model of traumatic brain injury. Acupunct Med. 2016;34:48-54 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100; fig 1
Basu S, Combe K, Kwiatkowski F, Caldefie Chézet F, Penault Llorca F, Bignon Y, et al. Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen. PLoS ONE. 2015;10:e0138443 pubmed publisher
  • western blot; human; 1:1000; fig s5
Leve F, Peres Moreira R, Binato R, Abdelhay E, Morgado Díaz J. LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways. PLoS ONE. 2015;10:e0139094 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 3
  • western blot; mouse; 1:1000; fig 3
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  • western blot; human; fig 4
Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X. Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling. Int J Gynecol Cancer. 2015;25:345-55 pubmed publisher
  • western blot; human
Ulanet D, Couto K, Jha A, Choe S, Wang A, Woo H, et al. Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition. PLoS ONE. 2014;9:e115144 pubmed publisher
  • immunocytochemistry; human; 1:100
Xie Y, Lu W, Liu S, Yang Q, Carver B, Li E, et al. Crosstalk between nuclear MET and SOX9/?-catenin correlates with castration-resistant prostate cancer. Mol Endocrinol. 2014;28:1629-39 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 7
  • immunohistochemistry - paraffin section; mouse; fig 6
Ostapoff K, Cenik B, Wang M, Ye R, Xu X, Nugent D, et al. Neutralizing murine TGF?R2 promotes a differentiated tumor cell phenotype and inhibits pancreatic cancer metastasis. Cancer Res. 2014;74:4996-5007 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Coulson Thomas V, Gesteira T, Esko J, KAO W. Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. J Biol Chem. 2014;289:25211-26 pubmed publisher
  • western blot; human; fig 6
Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, et al. Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer. J Pathol. 2014;234:302-15 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Konsavage W, Yochum G. The myc 3' wnt-responsive element suppresses colonic tumorigenesis. Mol Cell Biol. 2014;34:1659-69 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:800
Hilliard S, Yao X, El Dahr S. Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014;387:1-14 pubmed publisher
  • western blot; mouse; 1:1000
Nakamura I, Fernández Barrena M, Ortiz Ruiz M, Almada L, Hu C, Elsawa S, et al. Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration. J Biol Chem. 2013;288:21389-98 pubmed publisher
Pruitt H, Metge B, Weeks S, Chen D, Wei S, Kesterson R, et al. Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors. Oncogene. 2018;37:1610-1623 pubmed publisher
Batista Nascimento L, Neef D, Liu P, Rodrigues Pousada C, Thiele D. Deciphering human heat shock transcription factor 1 regulation via post-translational modification in yeast. PLoS ONE. 2011;6:e15976 pubmed publisher
product information
SKU :
9582S
Product-Name :
β-Catenin (6B3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (X, B, Dg, Pg, Hr)
Applications :
Immunohistochemistry (Frozen)
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
92
Host :
Rabbit
Target :
Catenin-beta
Primary-Protein :
CTNNB1
Alt-Names :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.