| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; loading ...; fig 6d
| Tian L, Chen C, Guo Y, Zhang F, Mi J, Feng Q, et al. mTORC2 regulates ribonucleotide reductase to promote DNA replication and gemcitabine resistance in non-small cell lung cancer. Neoplasia. 2021;23:643-652 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 4d
| Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig s1c
| Soleilhavoup C, Travaglio M, Patrick K, Garção P, Boobalan E, Adolfs Y, et al. Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020;11:3111 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 5a
| Gallo S, Spilinga M, Albano R, Ferrauto G, Di Gregorio E, Casanova E, et al. Activation of the MET receptor attenuates doxorubicin-induced cardiotoxicity in vivo and in vitro. Br J Pharmacol. 2020;177:3107-3122 pubmed publisher |
- immunocytochemistry; mouse; 1:500; loading ...; fig 3g
| Legrand J, Chan A, La H, Rossello F, Ankö M, Fuller Pace F, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2a
| Naito H, Iba T, Wakabayashi T, Tai Nagara I, Suehiro J, Jia W, et al. TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity. Dev Cell. 2019;48:151-166.e7 pubmed publisher |
- western blot; mouse; loading ...; fig s1g
| Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 5c
| Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau D, Zavala E, et al. NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. Proc Natl Acad Sci U S A. 2018;115:E1876-E1885 pubmed publisher |
- flow cytometry; mouse; loading ...; fig e6c
| Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 6c
| Hernández I, Torres Peraza J, Santos Galindo M, Ramos Morón E, Fernandez Fernandez M, Pérez Álvarez M, et al. The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease. Acta Neuropathol. 2017;134:839-850 pubmed publisher |
- western blot; human; fig 6c
| Sun H, Jiang M, Fu X, Cai Q, Zhang J, Yin Y, et al. Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells. Transl Neurodegener. 2017;6:12 pubmed publisher |
- immunohistochemistry; mouse; 1:200; loading ...; fig 2e
| Barazzuol L, Ju L, Jeggo P. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biol. 2017;15:e2001264 pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:400; loading ...; fig 11
| Pan S, Li S, Hu Y, Zhang H, Liu Y, Jiang H, et al. Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia. Oncotarget. 2016;7:79247-79261 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 3b
| Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed |
- immunohistochemistry; human; 1:500; loading ...; fig 4e
| Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed publisher |
- immunocytochemistry; human; loading ...; fig e2a
| Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher |
- immunohistochemistry; human; 1:100; loading ...; fig 4b
| Fang W, Yao M, Brummer G, Acevedo D, Alhakamy N, Berkland C, et al. Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment. Oncotarget. 2016;7:49349-49367 pubmed publisher |
- western blot; human; loading ...; fig 2f
| Huang J, CHEN C, Gu H, Li C, Fu X, Jiang M, et al. Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating GRP78 in SH-SY5Y cells. Cell Biol Int. 2016;40:803-11 pubmed publisher |
- immunohistochemistry; mouse; 1:100; fig s3
| Rios A, Fu N, Jamieson P, Pal B, Whitehead L, Nicholas K, et al. Essential role for a novel population of binucleated mammary epithelial cells in lactation. Nat Commun. 2016;7:11400 pubmed publisher |
- western blot; mouse; loading ...; fig 6g
| Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 5
| Nakagawa A, Adams C, Huang Y, Hamarneh S, Liu W, Von Alt K, et al. Selective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomains. Sci Rep. 2016;6:20390 pubmed publisher |
- western blot; mouse; loading ...; fig 7
| Wang Y, Xu S, Xu W, Yang H, Hu P, Li Y. Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells. Mol Med Rep. 2016;13:1111-8 pubmed publisher |
- immunohistochemistry; mouse; 1:400; loading ...; fig 2c
| Tronnes A, Koschnitzky J, Daza R, Hitti J, Ramirez J, Hevner R. Effects of Lipopolysaccharide and Progesterone Exposures on Embryonic Cerebral Cortex Development in Mice. Reprod Sci. 2016;23:771-8 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 1
| Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nat Med. 2015;21:1364-71 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 5
| Zaitoun I, Johnson R, Jamali N, Almomani R, Wang S, Sheibani N, et al. Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization. PLoS ONE. 2015;10:e0139994 pubmed publisher |
- western blot; mouse; fig s3
| Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher |
| Kao S, Stankovic K. Transactivation of human osteoprotegerin promoter by GATA-3. Sci Rep. 2015;5:12479 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 3a
| Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher |
- immunohistochemistry; mouse; fig 2
- western blot; mouse; fig 2
| Sykora P, Misiak M, Wang Y, Ghosh S, Leandro G, Liu D, et al. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res. 2015;43:943-59 pubmed publisher |
- immunocytochemistry; human; fig 2
| Kocher B, White L, Piwnica Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed publisher |
- immunohistochemistry; mouse; 1:200; loading ...; fig 5c,5d,6
| Jeitany M, Pineda J, Liu Q, Porreca R, Hoffschir F, Desmaze C, et al. A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT). Int J Cancer. 2015;136:1546-58 pubmed publisher |
| Nazari M, Serrill J, Wan X, Nguyen M, Anklin C, Gallegos D, et al. New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors. J Med Chem. 2017;60:7850-7862 pubmed publisher |
| Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed publisher |
| Chuang C, Greenside P, Rogers Z, Brady J, Yang D, Ma R, et al. Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Nat Med. 2017;23:291-300 pubmed publisher |
| Zhao Y, Tu M, Wang W, Qiu J, Yu A, Yu A. Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest. Sci Rep. 2016;6:26611 pubmed publisher |
| Kong D, Chen F, Sima N. Inhibition of focal adhesion kinase induces apoptosis in bladder cancer cells via Src and the phosphatidylinositol 3-kinase/Akt pathway. Exp Ther Med. 2015;10:1725-1731 pubmed |
| Barazzuol L, Rickett N, Ju L, Jeggo P. Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015;128:3597-606 pubmed publisher |
| Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed publisher |
| Sun S, Sun M, Zhang Y, Cheng C, Waqas M, Yu H, et al. In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period. Front Cell Neurosci. 2014;8:248 pubmed publisher |
| Abdi J, Garssen J, Faber J, Redegeld F. Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells. J Nutr Biochem. 2014;25:1254-62 pubmed publisher |
| Arboleda Velasquez J, Primo V, Graham M, James A, Manent J, D Amore P. Notch signaling functions in retinal pericyte survival. Invest Ophthalmol Vis Sci. 2014;55:5191-9 pubmed publisher |
| Abdi J, Mutis T, Garssen J, Redegeld F. Toll-like receptor (TLR)-1/2 triggering of multiple myeloma cells modulates their adhesion to bone marrow stromal cells and enhances bortezomib-induced apoptosis. PLoS ONE. 2014;9:e96608 pubmed publisher |
| Bryce S, Bemis J, Mereness J, Spellman R, Moss J, Dickinson D, et al. Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents. Environ Mol Mutagen. 2014;55:542-55 pubmed publisher |
| Migliardi G, Sassi F, Torti D, Galimi F, Zanella E, Buscarino M, et al. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas. Clin Cancer Res. 2012;18:2515-25 pubmed publisher |
