| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; mouse; 1:50; loading ...
| Kim S, Henneicke H, Cavanagh L, Macfarlane E, Thai L, Foong D, et al. Osteoblastic glucocorticoid signaling exacerbates high-fat-diet- induced bone loss and obesity. Bone Res. 2021;9:40 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s4d
| Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed publisher |
- other; mouse; 1:200; loading ...; fig s7b
- western blot; mouse; 1:1000; loading ...; fig 5a
| Beckmann D, Römer Hillmann A, Krause A, Hansen U, Wehmeyer C, Intemann J, et al. Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. Nat Commun. 2021;12:3624 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 3c
- western blot; mouse; loading ...; fig 1b, 6a
| Ianni A, Hofmann M, Kumari P, Tarighi S, Al tamari H, Görgens A, et al. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:639162 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig s3a
- immunocytochemistry; human; 1:400; loading ...; fig 2b
- western blot; human; 1:2000; loading ...; fig 2a
| Goswami S, Balasubramanian I, D Agostino L, Bandyopadhyay S, Patel R, Avasthi S, et al. RAB11A-mediated YAP localization to adherens and tight junctions is essential for colonic epithelial integrity. J Biol Chem. 2021;297:100848 pubmed publisher |
- western blot; human; 1:700; loading ...; fig 6
| Lee J, Hsu Y, Li Y, Cheng S. Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells. Int J Endocrinol. 2021;2021:5583491 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4d
- western blot; human; 1:1000; loading ...; fig s5a, s5b
| Wojnarowicz P, Escolano M, Huang Y, Desai B, Chin Y, Shah R, et al. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021;7:58 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Nam B, Park H, Lee Y, Oh Y, Park J, Kim S, et al. TGFβ1 Suppressed Matrix Mineralization of Osteoblasts Differentiation by Regulating SMURF1-C/EBPβ-DKK1 Axis. Int J Mol Sci. 2020;21: pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 1e
| Song M, YEKU O, Rafiq S, Purdon T, Dong X, Zhu L, et al. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Nat Commun. 2020;11:6298 pubmed publisher |
- western blot; human; 1:1000; fig s3h
| Wang H, Wang M, Wen Y, Xu C, Chen X, Wu D, et al. Biphasic Regulation of Mesenchymal Genes Controls Fate Switches During Hematopoietic Differentiation of Human Pluripotent Stem Cells. Adv Sci (Weinh). 2020;7:2001019 pubmed publisher |
- western blot; human; loading ...; fig 7b
| Liao T, Lin C, Jiang J, Yang S, Teng H, Yang M. Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer. Theranostics. 2020;10:6095-6112 pubmed publisher |
- western blot; human; loading ...; fig 5i
| Rinastiti P, Ikeda K, Rahardini E, Miyagawa K, Tamada N, Kuribayashi Y, et al. Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition. PLoS ONE. 2020;15:e0226049 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3f
- western blot; human; 1:1000; loading ...; fig 3i
| Zhu K, Lai Y, Cao H, Bai X, Liu C, Yan Q, et al. Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. Nat Commun. 2020;11:484 pubmed publisher |
- chromatin immunoprecipitation; mouse; 1:400; loading ...; fig 6h
| Chen M, Lu P, Ma Q, Cao Y, Chen N, Li W, et al. CTNNB1/β-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes. Sci Adv. 2020;6:eaax9605 pubmed publisher |
- immunoprecipitation; mouse; 1:500; fig 6b
| Jiang M, Kang Y, Sewastianik T, Wang J, Tanton H, Alder K, et al. BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins. Nat Commun. 2020;11:19 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5c
| Duhachek Muggy S, Bhat K, Medina P, Cheng F, He L, Alli C, et al. Radiation Mitigation of the Intestinal Acute Radiation Injury in Mice by 1-[(4-Nitrophenyl)Sulfonyl]-4-Phenylpiperazine. Stem Cells Transl Med. 2019;: pubmed publisher |
- western blot; human; loading ...; fig s2b
| Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2f
| Fearnley G, Young K, Edgar J, Antrobus R, Hay I, Liang W, et al. The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion. elife. 2019;8: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
- western blot; mouse; loading ...; fig 3a
| Bishnupuri K, Alvarado D, Khouri A, Shabsovich M, Chen B, Dieckgraefe B, et al. IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis. Cancer Res. 2019;: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6a
| Wang L, Chai Y, Li C, Liu H, Su W, Liu X, et al. Oxidized phospholipids are ligands for LRP6. Bone Res. 2018;6:22 pubmed publisher |
- western blot; mouse; 1:500-1:1000; loading ...; fig 3
| Suzuki S, Tanaka A, Nakamura H, Murayama T. Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis. Biol Pharm Bull. 2018;41:797-805 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5a
| Li Q, Ye L, Zhang X, Wang M, Lin C, Huang S, et al. FZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/β-catenin signaling. Cancer Lett. 2017;402:166-176 pubmed publisher |
- western blot; mouse; loading ...; fig 3g
| Matsumoto Y, La Rose J, Lim M, Adissu H, Law N, Mao X, et al. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. J Clin Invest. 2017;127:2612-2625 pubmed publisher |
- western blot; mouse; 1:50; fig 5b
| Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Nag J, Kancharla A, Maoz M, Turm H, Agranovich D, Gupta C, et al. Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated ?-catenin stabilization. Oncotarget. 2017;8:38650-38667 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 4C
| Hu X, Zhang Z, Liang Z, Xie D, Zhang T, Yu D, et al. Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma. Oncol Lett. 2017;13:686-694 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- immunocytochemistry; pigs ; 1:200; fig 2
| Palma Vera S, Schoen J, Chen S. Periovulatory follicular fluid levels of estradiol trigger inflammatory and DNA damage responses in oviduct epithelial cells. PLoS ONE. 2017;12:e0172192 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
| Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher |
- western blot; human; loading ...
| Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher |
- western blot; human; fig 3a
| Cao J, Tyburczy M, Moss J, Darling T, Widlund H, Kwiatkowski D. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. J Clin Invest. 2017;127:349-364 pubmed publisher |
- immunohistochemistry; mouse; fig 7b
- western blot; mouse; fig 7a
- immunohistochemistry; human; 1:100; fig 6c
- western blot; human; fig 6a
| Chu Q, Huang H, Huang T, Cao L, Peng L, Shi S, et al. Extracellular serglycin upregulates the CD44 receptor in an autocrine manner to maintain self-renewal in nasopharyngeal carcinoma cells by reciprocally activating the MAPK/β-catenin axis. Cell Death Dis. 2016;7:e2456 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s1a
| Salazar V, Ohte S, Capelo L, Gamer L, Rosen V. Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2. Development. 2016;143:4352-4367 pubmed |
- western blot; mouse; loading ...; fig 3a
| Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher |
- western blot; human; 1:1000; fig 5e
| Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher |
- immunohistochemistry; human; 1:100; loading ...; fig 2b
| Wang M, Nagle R, Knudsen B, Rogers G, Cress A. A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci. 2017;130:104-110 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 3
- western blot; mouse; fig 6
| Hsu Y, Chang P, Ho C, Huang Y, Shih Y, Wang C, et al. Protective effects of miR-29a on diabetic glomerular dysfunction by modulation of DKK1/Wnt/β-catenin signaling. Sci Rep. 2016;6:30575 pubmed publisher |
- western blot; human; loading ...; fig 6e
| Im J, Yoon S, Kim B, Ban H, Won K, Chung K, et al. DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes ?-catenin-mediated invasion. Biochim Biophys Acta. 2016;1859:1449-1458 pubmed publisher |
- western blot; human; fig 2
| Jung J, Kang K, Kim J, Hong S, Park Y, Kim B. CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, ?-Catenin, and hTERT Activities. Stem Cells Dev. 2016;25:1006-19 pubmed publisher |
- western blot; human; fig s5
- western blot; mouse; fig s1
| de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher |
- western blot; human; fig 1
| Chou C, Fan C, Lin P, Liao P, Tung J, Hsieh C, et al. Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis. Oncotarget. 2016;7:25742-54 pubmed publisher |
- immunocytochemistry; human; fig 1
| Kim J, Lee H, Park K, Choi Y, Nam J, Hong I. CWP232228 targets liver cancer stem cells through Wnt/β-catenin signaling: a novel therapeutic approach for liver cancer treatment. Oncotarget. 2016;7:20395-409 pubmed publisher |
- western blot; mouse; fig s10
| Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed A, Chen X, et al. Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway. Proc Natl Acad Sci U S A. 2016;113:1871-6 pubmed publisher |
- western blot; mouse; fig 5A
| Ou L, Fang L, Tang H, Qiao H, Zhang X, Wang Z. Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and in vivo. Mol Med Rep. 2016;13:720-30 pubmed publisher |
| Huang Y, Yang C, Wei P, Huynh T, Whang Peng J, Meng T, et al. Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways. J Hematol Oncol. 2017;10:60 pubmed publisher |
| Chen S, Palma Vera S, Langhammer M, Galuska S, Braun B, Krause E, et al. An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Sci Rep. 2017;7:42298 pubmed publisher |
| Fang Z, Zhang L, Liao Q, Wang Y, Yu F, Feng M, et al. Regulation of TRIM24 by miR-511 modulates cell proliferation in gastric cancer. J Exp Clin Cancer Res. 2017;36:17 pubmed publisher |
| Kendall J, Chaney K, Patel A, Rizvi T, Largaespada D, Ratner N. CK2 blockade causes MPNST cell apoptosis and promotes degradation of ?-catenin. Oncotarget. 2016;7:53191-53203 pubmed publisher |
| Chen G, Wang C, Wang J, Yin S, Gao H, Xiang L, et al. Antiosteoporotic effect of icariin in ovariectomized rats is mediated via the Wnt/?-catenin pathway. Exp Ther Med. 2016;12:279-287 pubmed |
| Hwang P, Jing L, Chen J, Lim F, Tang R, Choi H, et al. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. Sci Rep. 2016;6:28038 pubmed publisher |
| Oda K, Yatera K, Izumi H, Ishimoto H, Yamada S, Nakao H, et al. Profibrotic role of WNT10A via TGF-? signaling in idiopathic pulmonary fibrosis. Respir Res. 2016;17:39 pubmed publisher |
