product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-β-Catenin (Ser33/37/Thr41) Antibody
catalog :
9561
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, dogs, bovine, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, RNA immunoprecipitation
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; fig 6a
He W, Lu Q, Sherchan P, Huang L, Hu X, Zhang J, et al. Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice. Fluids Barriers CNS. 2021;18:44 pubmed publisher
  • western blot; human; loading ...; fig s4b
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 2e
Shen J, Sun Y, Liu X, Zhu Y, Bao B, Gao T, et al. EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling. Stem Cell Res Ther. 2021;12:415 pubmed publisher
  • western blot; human; loading ...; fig 5f
Jiang J, Li J, Yao W, Wang W, Shi B, Yuan F, et al. FOXC1 Negatively Regulates DKK1 Expression to Promote Gastric Cancer Cell Proliferation Through Activation of Wnt Signaling Pathway. Front Cell Dev Biol. 2021;9:662624 pubmed publisher
  • western blot; mouse; loading ...; fig 2d
Li X, Huang K, Liu X, Ruan H, Ma L, Liang J, et al. Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway. Front Pharmacol. 2021;12:639574 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Zhu X, Chen L, Huang B, Li X, Yang L, Hu X, et al. Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer. J Exp Clin Cancer Res. 2021;40:122 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a, 6c
Zhang L, Li M, Tian C, Wang T, Mi S. CCAAT enhancer binding protein α suppresses proliferation, metastasis, and epithelial-mesenchymal transition of ovarian cancer cells via suppressing the Wnt/β-catenin signaling. Neoplasma. 2021;68:602-612 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5c
Singh S, Adam M, Matkar P, Bugyei Twum A, Desjardins J, Chen H, et al. Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis. Sci Rep. 2020;10:4466 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 9b
Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed publisher
  • RNA immunoprecipitation; human; 1:500; loading ...; fig 6c
Hu Y, Zhao Y, Shi C, Ren P, Wei B, Guo Y, et al. A circular RNA from APC inhibits the proliferation of diffuse large B-cell lymphoma by inactivating Wnt/β-catenin signaling via interacting with TET1 and miR-888. Aging (Albany NY). 2019;11:8068-8084 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c, 2d
Ji L, Lu B, Wang Z, Yang Z, Reece Hoyes J, Russ C, et al. Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction. Mol Cell. 2018;72:37-47.e4 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s4a
Li Q, Ye L, Zhang X, Wang M, Lin C, Huang S, et al. FZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/β-catenin signaling. Cancer Lett. 2017;402:166-176 pubmed publisher
  • western blot; human; loading ...; fig 4b
Choi E, Jung B, Lee S, Yoo H, Shin E, Ko H, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017;36:5285-5295 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  • western blot; pigs ; loading ...; fig 2a
Genovese N, Domeier T, Telugu B, Roberts R. Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells. Sci Rep. 2017;7:41833 pubmed publisher
  • western blot; mouse; 1:1000; fig 3d
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, et al. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo. Oncotarget. 2016;7:63730-63746 pubmed publisher
  • western blot; human; 1:1000; fig 2
Fang F, Qin Y, Hao F, Li Q, Zhang W, Zhao C, et al. CD147 modulates androgen receptor activity through the Akt/Gsk-3?/?-catenin/AR pathway in prostate cancer cells. Oncol Lett. 2016;12:1124-1128 pubmed
  • western blot; human; fig s1b
Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/?-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7:42513-42526 pubmed publisher
  • western blot; human; fig 3
Kuang J, Li L, Guo L, Su Y, Wang Y, Xu Y, et al. RNF8 promotes epithelial-mesenchymal transition of breast cancer cells. J Exp Clin Cancer Res. 2016;35:88 pubmed publisher
  • western blot; human; loading ...; fig 4b
Lubeseder Martellato C, Hidalgo Sastre A, Hartmann C, Alexandrow K, Kamyabi Moghaddam Z, Sipos B, et al. Membranous CD24 drives the epithelial phenotype of pancreatic cancer. Oncotarget. 2016;7:49156-49168 pubmed publisher
  • western blot; mouse; fig 6
Illich D, Zhang M, Ursu A, Osorno R, Kim K, Yoon J, et al. Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Rep. 2016;15:787-800 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25; fig s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Ye S, Zhang D, Cheng F, Wilson D, Mackay J, He K, et al. Wnt/β-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. J Cell Sci. 2016;129:269-76 pubmed publisher
  • western blot; mouse; fig s1
Akhade V, Dighe S, Kataruka S, Rao M. Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells. Nucleic Acids Res. 2016;44:387-401 pubmed publisher
  • immunocytochemistry; human; 1:200
Vestergaard M, Awan A, Warzecha C, Christensen S, Andersen C. Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways. Methods Mol Biol. 2016;1307:123-40 pubmed publisher
Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed publisher
product information
SKU :
9561S
Product-Name :
Phospho-β-Catenin (Ser33/37/Thr41) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, (C, X, Z, B, Dg, Pg)
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
92
Host :
Rabbit
Target :
Catenin-beta (Ser33/Ser37/Thr41) phosphate
Primary-Protein :
CTNNB1
Alt-Names :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.