product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PDCD4 (D29C6) XP® Rabbit mAb
catalog :
9535
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D29C6
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Lingel H, Wissing J, Arra A, Schanze D, Lienenklaus S, Klawonn F, et al. CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation. Cell Death Differ. 2017;24:1739-1749 pubmed publisher
  • western blot; mouse; loading ...; fig 6d
He W, Wang C, Mu R, Liang P, Huang Z, Zhang J, et al. MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles. Oncogene. 2017;36:4212-4223 pubmed publisher
  • immunocytochemistry; mouse; 1:300; fig 3
  • western blot; mouse; 1:1000; fig 5
Bai Y, Dong Z, Shang Q, Zhao H, Wang L, Guo C, et al. Pdcd4 Is Involved in the Formation of Stress Granule in Response to Oxidized Low-Density Lipoprotein or High-Fat Diet. PLoS ONE. 2016;11:e0159568 pubmed publisher
  • western blot; human; loading ...; fig 5a
Li Y, Jiang D, Zhang Q, Liu X, Cai Z. Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4. Int J Mol Med. 2016;38:803-11 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 7a
  • western blot; human; 1:1000; loading ...; fig 2a
Maachani U, Tandle A, Shankavaram U, Kramp T, Camphausen K. Modulation of miR-21 signaling by MPS1 in human glioblastoma. Oncotarget. 2016;7:52912-52927 pubmed publisher
  • western blot; human; fig 4d
Schipany K, Rosner M, Ionce L, Hengstschläger M, Kovacic B. eIF3 controls cell size independently of S6K1-activity. Oncotarget. 2015;6:24361-75 pubmed
  • western blot; human
Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed publisher
  • immunoprecipitation; human
Xu H, Dephoure N, Sun H, Zhang H, Fan F, Liu J, et al. Proteomic Profiling of Paclitaxel Treated Cells Identifies a Novel Mechanism of Drug Resistance Mediated by PDCD4. J Proteome Res. 2015;14:2480-91 pubmed publisher
  • western blot; mouse
Galicia Vázquez G, Di Marco S, Lian X, Ma J, Gallouzi I, Pelletier J. Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation. PLoS ONE. 2014;9:e87237 pubmed publisher
  • western blot; mouse; 1:1000
Ma X, Choudhury S, Hua X, Dai Z, Li Y. Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Carcinogenesis. 2013;34:1216-23 pubmed publisher
Chen Z, Yuan Y, Wang Y, Liu Z, Chan H, Chen S. Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer. Breast Cancer Res Treat. 2015;152:29-39 pubmed publisher
Brønnum H, Andersen D, Schneider M, Sandberg M, Eskildsen T, Nielsen S, et al. miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS ONE. 2013;8:e56280 pubmed publisher
Yen W, Fischer M, Hynes M, Wu J, Kim E, Beviglia L, et al. Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells. Clin Cancer Res. 2012;18:5374-86 pubmed publisher
product information
SKU :
9535S
Product-Name :
PDCD4 (D29C6) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
PDCD4
Primary-Protein :
PDCD4
Alt-Names :
H731,MGC33046,MGC33047,Neoplastic transformation inhibitor protein,Nuclear antigen H731-like,PDCD4,Programmed cell death protein 4,Protein 197/15a,nuclear antigen H731,programmed cell death 4,programmed cell death 4 (neoplastic transformation inhibitor)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.