| Published Application/Species/Dilution | Reference |
|---|
- western blot (knockdown validation); rat; fig 5
| Hesler R, Huang J, Starr M, Treboschi V, Bernanke A, Nixon A, et al. TGF-β-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3. Carcinogenesis. 2016;: pubmed |
- western blot; human; 1:1000; fig s5
| Cammareri P, Rose A, Vincent D, Wang J, Nagano A, Libertini S, et al. Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma. Nat Commun. 2016;7:12493 pubmed publisher |
- immunocytochemistry; human; fig s10
| Chang H, Liu Y, Xue M, Liu H, Du S, Zhang L, et al. Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition. Nucleic Acids Res. 2016;44:2514-27 pubmed publisher |
- western blot; mouse; fig 5
| Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher |
| Faura Tellez G, Vandepoele K, Brouwer U, Koning H, Elderman R, Hackett T, et al. Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription. Am J Physiol Lung Cell Mol Physiol. 2015;309:L725-35 pubmed publisher |
- chromatin immunoprecipitation; mouse; 1:50; fig 1d
| Feuerborn A, Mathow D, Srivastava P, Gretz N, Grone H. Basonuclin-1 modulates epithelial plasticity and TGF-β1-induced loss of epithelial cell integrity. Oncogene. 2015;34:1185-95 pubmed publisher |
- chromatin immunoprecipitation; mouse; fig s15
- proximity ligation assay; mouse; fig s12
| Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed publisher |
- western blot; mouse; 1:1000; fig 7
| Tontonoz P, Cortez-Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, et al. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015;35:1125-38 pubmed publisher |
- western blot; human; 1:1000; fig 7
| Zhou X, Tao Y, Liang C, Zhang Y, Li H, Chen Q. BMP3 Alone and Together with TGF-β Promote the Differentiation of Human Mesenchymal Stem Cells into a Nucleus Pulposus-Like Phenotype. Int J Mol Sci. 2015;16:20344-59 pubmed publisher |
- western blot; mouse; 1:1000; fig 7
| Das R, Xu S, Quan X, Nguyen T, Kong I, Chung C, et al. Upregulation of mitochondrial Nox4 mediates TGF-β-induced apoptosis in cultured mouse podocytes. Am J Physiol Renal Physiol. 2014;306:F155-67 pubmed publisher |
- western blot; mouse; 1:1000
| Watatani H, Maeshima Y, Hinamoto N, Yamasaki H, Ujike H, Tanabe K, et al. Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction. Physiol Rep. 2014;2: pubmed publisher |
| Yi X, Li X, Zhou Y, Ren S, Wan W, Feng G, et al. Hepatocyte growth factor regulates the TGF-β1-induced proliferation, differentiation and secretory function of cardiac fibroblasts. Int J Mol Med. 2014;34:381-90 pubmed publisher |
- western blot; mouse; fig 2,3
| Flanders K, Heger C, Conway C, Tang B, Sato M, Dengler S, et al. Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections. J Histochem Cytochem. 2014;62:846-63 pubmed publisher |
- western blot; human; fig 1
| Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed publisher |
| Beaudoin M, Snook L, Arkell A, Stefanson A, Wan Z, Simpson J, et al. Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats. Obesity (Silver Spring). 2014;22:1632-42 pubmed publisher |
- western blot; mouse; fig 6
| Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed publisher |
| Li Y, Klausen C, Cheng J, Zhu H, Leung P. Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin. J Clin Endocrinol Metab. 2014;99:E2216-25 pubmed publisher |
| Kasai A, Ishimaru Y, Higashino K, Kobayashi K, Yamamuro A, Yoshioka Y, et al. Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis. Angiogenesis. 2013;16:723-34 pubmed publisher |
| Guo Z, Khattar M, Schroder P, Miyahara Y, Wang G, He X, et al. A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells. J Immunol. 2013;190:3153-62 pubmed publisher |
| Nakamura K, Nakano S, Miyoshi T, Yamanouchi K, Nishihara M. Loss of SPARC in mouse skeletal muscle causes myofiber atrophy. Muscle Nerve. 2013;48:791-9 pubmed publisher |
| Louafi F, Martinez-Nunez R, Sanchez-Elsner T. MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem. 2010;285:41328-36 pubmed publisher |
| Li Q, Pangas S, Jorgez C, Graff J, Weinstein M, Matzuk M. Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. Mol Cell Biol. 2008;28:7001-11 pubmed publisher |
| Sarközi R, Flucher K, Haller V, Pirklbauer M, Mayer G, Schramek H. Oncostatin M inhibits TGF-β1-induced CTGF expression via STAT3 in human proximal tubular cells. Biochem Biophys Res Commun. 2012;424:801-6 pubmed publisher |
| Xu B, Chen H, Xu W, Zhang W, Buckley S, Zheng S, et al. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2012;303:L89-96 pubmed publisher |
