product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Smad5 Antibody
catalog :
9517
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 3
Watanabe Y, Papoutsoglou P, Maturi V, Tsubakihara Y, Hottiger M, Heldin C, et al. Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation. J Biol Chem. 2016;291:12706-23 pubmed publisher
  • western blot; human; 1:1000; fig s1
Krishnan S, Szabo E, Burghardt I, Frei K, Tabatabai G, Weller M. Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition. Oncotarget. 2015;6:22480-95 pubmed
  • immunocytochemistry; mouse; loading ...; fig 1c
  • western blot; mouse; loading ...; fig 4c
Marks Bluth J, Khanna A, Chandrakanthan V, Thoms J, Bee T, Eich C, et al. SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development. Mol Cell Biol. 2015;35:2165-72 pubmed publisher
  • western blot; mouse; loading ...; fig 3b
Ruan X, Zuo Q, Jia H, Chau J, Lin J, Ao J, et al. P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers. J Mol Cell Biol. 2015;7:105-18 pubmed publisher
  • western blot; human
Perna F, Vu L, Themeli M, Kriks S, Hoya Arias R, Khanin R, et al. The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem Cell Reports. 2015;4:658-69 pubmed publisher
  • western blot; human; 1:1000; fig 5
Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu Kaoud N, Halabi N, et al. Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med. 2015;13:27 pubmed publisher
  • western blot; mouse; fig 2,3
Flanders K, Heger C, Conway C, Tang B, Sato M, Dengler S, et al. Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections. J Histochem Cytochem. 2014;62:846-63 pubmed publisher
  • western blot; rat; 1:500
Borkham Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-? signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed publisher
  • western blot; human; fig 1
Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed publisher
Thomas J, Eric Dollins D, Andrykovich K, Chu T, Stultz B, Hursh D, et al. SMOC can act as both an antagonist and an expander of BMP signaling. elife. 2017;6: pubmed publisher
Asperti M, Stuemler T, Poli M, Gryzik M, Lifshitz L, Meyron Holtz E, et al. Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation. PLoS ONE. 2016;11:e0164183 pubmed publisher
Yeung C, Gossan N, Lu Y, Hughes A, Hensman J, Bayer M, et al. Gremlin-2 is a BMP antagonist that is regulated by the circadian clock. Sci Rep. 2014;4:5183 pubmed publisher
Ng K, Lee Y, Lai W, Chan Y, Fung M, Tse H, et al. Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells. PLoS ONE. 2011;6:e19787 pubmed publisher
product information
SKU :
9517P
Product-Name :
Smad5 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, R, Mk
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
60
Host :
Rabbit
Target :
Smad5
Primary-Protein :
Smad5
Alt-Names :
DKFZp781C1895,DKFZp781O1323,Dwfc,JV5-1,MAD homolog 5,MAD, mothers against decapentaplegic homolog 5,MADH5,Mothers against DPP homolog 5,Mothers against decapentaplegic homolog 5,SMA- and MAD-related protein 5,SMAD 5,SMAD family member 5,SMAD, mothers against DPP homolog 5,SMAD5,hSmad5,mothers against decapentaplegic, drosophila, homolog of, 5
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.