product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb
catalog :
9516P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 18
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Micha D, Voermans E, Eekhoff M, van Essen H, Zandieh-Doulabi B, Netelenbos C, et al. Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease. Bone. 2016;84:169-80 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 1
  • western blot; mouse; 1:1000; fig s4
Pickup M, Hover L, Guo Y, Gorska A, Chytil A, Novitskiy S, et al. Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis. Oncotarget. 2015;6:22890-904 pubmed
  • western blot; mouse
Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells. 2015;33:742-50 pubmed publisher
  • western blot; mouse; 1:1000
Tian E, Stevens S, Guan Y, Springer D, Anderson S, Starost M, et al. Galnt1 is required for normal heart valve development and cardiac function. PLoS ONE. 2015;10:e0115861 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Chung D, Gao F, Jegga A, Das S. Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a. Mol Cell Endocrinol. 2015;400:48-60 pubmed publisher
  • western blot; rat; 1:1000; fig 8
Sun J, Li J, Li C, Yu Y. Role of bone morphogenetic protein-2 in osteogenic differentiation of mesenchymal stem cells. Mol Med Rep. 2015;12:4230-7 pubmed publisher
  • western blot; mouse
Kim J, Shim M. Prostaglandin F2α receptor (FP) signaling regulates Bmp signaling and promotes chondrocyte differentiation. Biochim Biophys Acta. 2015;1853:500-12 pubmed publisher
  • western blot; human
Perna F, Vu L, Themeli M, Kriks S, Hoya-Arias R, Khanin R, et al. The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem Cell Reports. 2015;4:658-69 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Gu S, Wu W, Liu C, Yang L, Sun C, Ye W, et al. BMPRIA mediated signaling is essential for temporomandibular joint development in mice. PLoS ONE. 2014;9:e101000 pubmed publisher
  • immunohistochemistry; rat; 1:1500; fig 4
Scholze A, Foo L, Mulinyawe S, Barres B. BMP signaling in astrocytes downregulates EGFR to modulate survival and maturation. PLoS ONE. 2014;9:e110668 pubmed publisher
  • western blot; human; 1:2000
Ren G, Beech C, Smas C. The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion. PLoS ONE. 2013;8:e65531 pubmed publisher
Massouridès E, Polentes J, Mangeot P, Mournetas V, Nectoux J, Deburgrave N, et al. Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells. Skelet Muscle. 2015;5:40 pubmed publisher
Weeks O, Bhullar B, Abzhanov A. Molecular characterization of dental development in a toothed archosaur, the American alligator Alligator mississippiensis. Evol Dev. 2013;15:393-405 pubmed publisher
Dai X, Jiang W, Zhang Q, Xu L, Geng P, Zhuang S, et al. Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 2013;11:107 pubmed publisher
Steensma M, Tyler W, Shaber A, Goldring S, Ross F, Williams B, et al. Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategy. PLoS ONE. 2013;8:e69101 pubmed publisher
Wu Y, Ai Z, Yao K, Cao L, Du J, Shi X, et al. CHIR99021 promotes self-renewal of mouse embryonic stem cells by modulation of protein-encoding gene and long intergenic non-coding RNA expression. Exp Cell Res. 2013;319:2684-99 pubmed publisher
Takahashi A, Morita M, Yokoyama K, Suzuki T, Yamamoto T. Tob2 inhibits peroxisome proliferator-activated receptor γ2 expression by sequestering Smads and C/EBPα during adipocyte differentiation. Mol Cell Biol. 2012;32:5067-77 pubmed publisher
Kosinski C, Stange D, Xu C, Chan A, Ho C, Yuen S, et al. Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development. Gastroenterology. 2010;139:893-903 pubmed publisher
product information
SKU :
9516P
Product-Name :
Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Smad1 (Ser463/Ser465) phosphate/Smad5 (Ser463/Ser465) phosphate
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.