product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cbl-b (D3C12) Rabbit mAb
catalog :
9498
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D3C12
reactivity :
human, mouse, rat, cow
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 1
Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck M, et al. A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. Oncotarget. 2016;7:51107-51123 pubmed publisher
  • western blot; human; fig 8c
Robles Valero J, Lorenzo Martín L, Menacho Márquez M, Fernández Pisonero I, Abad A, Camos M, et al. A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2017;32:608-623.e9 pubmed publisher
  • western blot; human; loading ...; fig 7
Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor ? (PDGFR?) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  • western blot; human
Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
product information
SKU :
9498S
Product-Name :
Cbl-b (D3C12) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B)
Applications :
Western blot
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
125, 130
Host :
Rabbit
Target :
Cbl-b
Primary-Protein :
Cbl-b
Alt-Names :
CBLB,Cas-Br-M (murine) ecotropic retroviral transforming sequence b,Cas-Br-M (murine) ectropic retroviral transforming sequence b,Casitas B-lineage lymphoma proto-oncogene b,DKFZp686J10223,DKFZp779A0729,DKFZp779F1443,E3 ubiquitin-protein ligase CBL-B,FLJ36865,FLJ41152,Nbla00127,RING finger protein 56,RNF56,SH3-binding protein CBL-B,Signal transduction protein CBL-B
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.