| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 1i
| Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella J, et al. Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia. Nat Commun. 2021;12:2482 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Chiu C, Weng Y, Huang Y, Chen R, Liu Y, Yeh T, et al. (D620N) VPS35 causes the impairment of Wnt/β-catenin signaling cascade and mitochondrial dysfunction in a PARK17 knockin mouse model. Cell Death Dis. 2020;11:1018 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Han B, Meng X, Wu P, Li Z, Li S, Zhang Y, et al. ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma. Theranostics. 2020;10:3351-3365 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 1e
| Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher |
- western blot; human; loading ...; fig s1a
| Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6a
| Sun J, Zhang X, Sun Y, Tang Z, Guo D. Effects of Hylomecon vernalis ethanol extracts on cell cycle and apoptosis of colon cancer cells. Mol Med Rep. 2017;15:3485-3492 pubmed publisher |
- western blot; human; loading ...; fig 3
| Jelinek M, Kabelova A, Srámek J, Seitz J, Ojima I, Kovar J. Differing Mechanisms of Death Induction by Fluorinated Taxane SB-T-12854 in Breast Cancer Cells. Anticancer Res. 2017;37:1581-1590 pubmed |
- western blot; human; loading ...; fig 2b
| Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed |
- immunohistochemistry - paraffin section; human; 1:50; fig 7
- western blot; human; 1:1000; fig s15
| Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher |
- western blot; human; loading ...; fig 5g
| Wu J, Lei H, Zhang J, Chen X, Tang C, Wang W, et al. Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation. Oncotarget. 2016;7:58995-59005 pubmed publisher |
- western blot; human; 1:500
| Cheng Y, Huang C, Lee Y, Tien L, Ku W, Chien R, et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016;6:30314 pubmed publisher |
- western blot; human; fig 2
| Helmke C, Raab M, Rodel F, Matthess Y, Oellerich T, Mandal R, et al. Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Res. 2016;26:914-34 pubmed publisher |
- western blot; human; fig 2
| Choi H, Kim M, Choi Y, Shin Y, Cho S, Ko S. Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation. BMC Complement Altern Med. 2016;16:122 pubmed publisher |
- western blot; human; fig 5
| Gao X, Feng J, He Y, Xu F, Fan X, Huang W, et al. hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep. 2016;6:22999 pubmed publisher |
- western blot; human; fig 5
| Natarelli L, Ranaldi G, Leoni G, Roselli M, Guantario B, Comitato R, et al. Nanomolar Caffeic Acid Decreases Glucose Uptake and the Effects of High Glucose in Endothelial Cells. PLoS ONE. 2015;10:e0142421 pubmed publisher |
- western blot; human; fig 5
| Shen W, Chang A, Wang J, Zhou W, Gao R, Li J, et al. TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer. Oncogenesis. 2015;4:e173 pubmed publisher |
| Li X, Liang Q, Liu W, Zhang N, Xu L, Zhang X, et al. Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. Oncogene. 2016;35:2453-64 pubmed publisher |
- western blot; human; fig 3
| Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed |
- western blot; human; fig s5a
| Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, et al. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. PLoS ONE. 2015;10:e0125381 pubmed publisher |
| Yanagi T, Shi R, Aza Blanc P, Reed J, Matsuzawa S. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PLoS ONE. 2015;10:e0119404 pubmed publisher |
| Shen X, Sun W, Shi Y, Xing Z, Su X. Altered viral replication and cell responses by inserting microRNA recognition element into PB1 in pandemic influenza A virus (H1N1) 2009. Mediators Inflamm. 2015;2015:976575 pubmed publisher |
- western blot; human; fig 3
| Long J, Schoonen P, Graczyk D, O Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed publisher |
- western blot; human; 1:1000; fig 8A
| Silva V, Plooster M, Leung J, Cassimeris L. A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells. Cell Cycle. 2015;14:1070-81 pubmed publisher |
- western blot; human; 1:10; fig 4
| Kang C, Lin J, Xu Z, Kumar S, Herr A. Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response. Anal Chem. 2014;86:10429-36 pubmed publisher |
| Zhang S, Tang W, Weng S, Liu X, Rao B, Gu J, et al. Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. Oncotarget. 2014;5:7183-97 pubmed |
| Derangère V, Chevriaux A, Courtaut F, Bruchard M, Berger H, Chalmin F, et al. Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells. Cell Death Differ. 2014;21:1914-24 pubmed publisher |
- western blot; human; 1:1000
| Ishikawa K, Saiki S, Furuya N, Yamada D, Imamichi Y, Li Y, et al. P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway. PLoS ONE. 2014;9:e94645 pubmed publisher |
- flow cytometry; human
- western blot; human
| Villa Morales M, Cobos M, González Gugel E, Alvarez Iglesias V, Martinez B, Piris M, et al. FAS system deregulation in T-cell lymphoblastic lymphoma. Cell Death Dis. 2014;5:e1110 pubmed publisher |
| Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher |
| Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis. 2014;5:e1043 pubmed publisher |
| Chopra A, Anderson A, Giardina C. Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis. J Biol Chem. 2014;289:2978-91 pubmed publisher |
| Linderoth E, Pilia G, Mahajan N, Ferby I. Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death. J Biol Chem. 2013;288:32922-31 pubmed publisher |
- immunocytochemistry; human
- western blot; human
| Sung M, Giannakakou P. BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling. Oncogene. 2014;33:1418-28 pubmed publisher |
| Han J, Soletti R, Sadarangani A, Sridevi P, Ramirez M, Eckmann L, et al. Nuclear expression of ?-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res. 2013;11:207-18 pubmed publisher |
- western blot; human; 1:1000
| Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
- western blot; human; 1:1000
| Gauster M, Siwetz M, Huppertz B. Fusion of villous trophoblast can be visualized by localizing active caspase 8. Placenta. 2009;30:547-50 pubmed publisher |
| Chen C, Dienhart J, Bolton E. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells. PLoS ONE. 2016;11:e0156145 pubmed publisher |
| Lam W, Jiang Z, Guan F, Huang X, Hu R, Wang J, et al. PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment. Sci Rep. 2015;5:9384 pubmed publisher |
| Knievel J, Schulz W, Greife A, Hader C, Lübke T, Schmitz I, et al. Multiple mechanisms mediate resistance to sorafenib in urothelial cancer. Int J Mol Sci. 2014;15:20500-17 pubmed publisher |
| Shu Q, Li W, Li H, Sun G. Vasostatin inhibits VEGF-induced endothelial cell proliferation, tube formation and induces cell apoptosis under oxygen deprivation. Int J Mol Sci. 2014;15:6019-30 pubmed publisher |
| Franco R, Bortner C, Schmitz I, Cidlowski J. Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1. Apoptosis. 2014;19:117-34 pubmed publisher |
| Peter B, Cerny Reiterer S, Hadzijusufovic E, Schuch K, Stefanzl G, Eisenwort G, et al. The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells. J Leukoc Biol. 2014;95:95-104 pubmed publisher |
| Foreman K, Jesse J, Kuo P, Gupta G. Emetine dihydrochloride: a novel therapy for bladder cancer. J Urol. 2014;191:502-9 pubmed publisher |
| Gao X, Lin J, Ning Q, Gao L, Yao Y, Zhou J, et al. A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells. PLoS ONE. 2013;8:e55481 pubmed publisher |
| Thomé C, Dos Santos G, Ferreira G, Scheucher P, Izumi C, Leopoldino A, et al. Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity. Mol Cell Proteomics. 2012;11:1898-912 pubmed publisher |
| Stutz N, Johnson R, Wood G. The Fas apoptotic pathway in cutaneous T-cell lymphomas: frequent expression of phenotypes associated with resistance to apoptosis. J Am Acad Dermatol. 2012;67:1327.e1-10 pubmed publisher |
| Jinesh G G, Chunduru S, Kamat A. Smac mimetic enables the anticancer action of BCG-stimulated neutrophils through TNF-? but not through TRAIL and FasL. J Leukoc Biol. 2012;92:233-44 pubmed publisher |
| Ghanim V, Herrmann H, Heller G, Peter B, Hadzijusufovic E, Blatt K, et al. 5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand. Blood. 2012;119:4242-52 pubmed publisher |
| D Agostino L, Giordano A. A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. Oncotarget. 2011;2:1055-74 pubmed |
| Henrich C, Thomas C, Brooks A, Booth N, Lowery E, Pompei R, et al. Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. Apoptosis. 2012;17:79-89 pubmed publisher |
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| Wu Y, Alvarez M, Slamon D, Koeffler P, Vadgama J. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer. 2010;10:32 pubmed publisher |
