product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Caspase-7 Antibody
catalog :
9492
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 5a
McComb S, Chan P, Guinot A, Hartmannsdottir H, Jenni S, Dobay M, et al. Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7. Sci Adv. 2019;5:eaau9433 pubmed publisher
  • western blot; human; loading ...; fig 2b
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed publisher
  • western blot; human; loading ...; fig 1b
Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5e
Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1g
Thurston T, Matthews S, Jennings E, Alix E, Shao F, Shenoy A, et al. Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun. 2016;7:13292 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; 1:1000; fig 3
Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed publisher
  • western blot; mouse; fig S3
Megyesi J, Tarcsafalvi A, Seng N, Hodeify R, Price P. Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak. Cell Death Discov. 2016;2: pubmed
  • western blot; human; 1:500; fig 4f
Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed publisher
  • western blot; human; fig 4b
Fedorenko I, Abel E, Koomen J, Fang B, Wood E, Chen Y, et al. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells. Oncogene. 2016;35:1225-35 pubmed publisher
Zhu Z, Tran H, Mathahs M, Moninger T, Schmidt W. HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes. PLoS ONE. 2017;12:e0166853 pubmed publisher
Trino S, Iacobucci I, Erriquez D, Laurenzana I, De Luca L, Ferrari A, et al. Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients. Oncotarget. 2016;7:12951-61 pubmed publisher
Yun T, Yu K, Yang S, Cui Y, Wang Z, Ren H, et al. Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway. J Biol Chem. 2016;291:7386-95 pubmed publisher
product information
SKU :
9492P
Product-Name :
Caspase-7 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
20, 35
Host :
Rabbit
Target :
Casp7
Primary-Protein :
Casp7
Alt-Names :
Apoptotic protease Mch-3,CASP-7,CASP7,CMH-1,Caspase-7,Caspase-7 subunit p11,Caspase-7 subunit p20,ICE-LAP3,ICE-like apoptotic protease 3,Lice2 alpha/beta/gamma,MCH3,caspase 7 isoform delta,caspase 7, apoptosis-related cysteine peptidase,caspase 7, apoptosis-related cysteine protease
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.