| Published Application/Species/Dilution | Reference |
|---|
| Ma P, Foote D, Sinnamon A, Brass L. Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1). PLoS ONE. 2015;10:e0119496 pubmed publisher |
| Gresa-Arribas N, Ariño H, Martinez-Hernandez E, Petit-Pedrol M, Sabater L, Saiz A, et al. Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity. PLoS ONE. 2015;10:e0121364 pubmed publisher |
| Wang Y, Zhang Y, Zhu Y, Zhang P. Lipolytic inhibitor G0/G1 switch gene 2 inhibits reactive oxygen species production and apoptosis in endothelial cells. Am J Physiol Cell Physiol. 2015;308:C496-504 pubmed publisher |
| Matsuno M, Horiuchi J, Yuasa Y, Ofusa K, Miyashita T, Masuda T, et al. Long-term memory formation in Drosophila requires training-dependent glial transcription. J Neurosci. 2015;35:5557-65 pubmed publisher |
| Yu F, Gao W, Yokochi T, Suenaga Y, Ando K, Ohira M, et al. RUNX3 interacts with MYCN and facilitates protein degradation in neuroblastoma. Oncogene. 2014;33:2601-9 pubmed publisher |
| Verma P, Pfister J, Mallick S, D'MELLO S. HSF1 protects neurons through a novel trimerization- and HSP-independent mechanism. J Neurosci. 2014;34:1599-612 pubmed publisher |
| Choi M, Nakamura T, Cho S, Han X, Holland E, Qu J, et al. Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models. J Neurosci. 2014;34:15123-31 pubmed publisher |
| Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher |
| Horbach T, Chi T, Götz C, Sharma S, Juffer A, Dimova E, et al. GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2. PLoS ONE. 2014;9:e107914 pubmed publisher |
| Hsu T, Hsiao H, Wu P, Liu W, Lai M. Deltex1 promotes protein kinase Cθ degradation and sustains Casitas B-lineage lymphoma expression. J Immunol. 2014;193:1672-80 pubmed publisher |
| Alcántara-Hernández R, Hernández-Méndez A, García-Sáinz J. The phosphoinositide-dependent protein kinase 1 inhibitor, UCN-01, induces fragmentation: possible role of metalloproteinases. Eur J Pharmacol. 2014;740:88-96 pubmed publisher |
| Tsai C, Larson C, Safaei R, Howell S. Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4. Biochem Pharmacol. 2014;90:379-87 pubmed publisher |
| Santiago Lima A, Hoogeveen-Westerveld M, Nakashima A, Maat-Kievit A, van den Ouweland A, Halley D, et al. Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complex. PLoS ONE. 2014;9:e93940 pubmed publisher |
| Yu F, Hong Y, Qu J, Chen F, Li T. The large intracellular loop of ptch1 mediates the non-canonical Hedgehog pathway through cyclin B1 in nevoid basal cell carcinoma syndrome. Int J Mol Med. 2014;34:507-12 pubmed publisher |
| Hattori T, Uchida C, Takahashi H, Yamamoto N, Naito M, Taya Y. Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells. PLoS ONE. 2014;9:e86709 pubmed publisher |
| Ali M, Chernova T, Newnam G, Yin L, Shanks J, Karpova T, et al. Stress-dependent proteolytic processing of the actin assembly protein Lsb1 modulates a yeast prion. J Biol Chem. 2014;289:27625-39 pubmed publisher |
| Chen X, Chinchilla P, Fombonne J, Ho L, Guix C, Keen J, et al. Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog. Mol Cell Biol. 2014;34:3855-66 pubmed publisher |
| Herbáth M, Szekeres Z, Kovesdi D, Papp K, Erdei A, Prechl J. Coadministration of antigen-conjugated and free CpG: effects of in vitro and in vivo interactions in a murine model. Immunol Lett. 2014;160:178-85 pubmed publisher |
| Murakami Y, Tian L, Voss O, Margulies D, Krzewski K, Coligan J. CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition. Cell Death Differ. 2014;21:1746-57 pubmed publisher |
| Jo C, Kim S, Cho S, Choi K, Yun S, Koh Y, et al. Sulforaphane induces autophagy through ERK activation in neuronal cells. FEBS Lett. 2014;588:3081-8 pubmed publisher |
| Cheung H, Dunbar C, Mórotz G, Cheng W, Chan H, Miller C, et al. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J. 2014;28:337-49 pubmed publisher |
| Han L, Diehl A, Nguyen N, Korangath P, Teo W, Cho S, et al. The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. Cancer Res. 2014;74:6509-18 pubmed publisher |
| Wu Y, Kuo W, Wu Y, Yang K, Chen S, Jiang S, et al. Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation. Cell Death Differ. 2014;21:451-61 pubmed publisher |
| Prox J, Willenbrock M, Weber S, Lehmann T, Schmidt-Arras D, Schwanbeck R, et al. Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10. Cell Mol Life Sci. 2012;69:2919-32 pubmed publisher |
| Pratt Z, Zhang J, Sugden B. The latent membrane protein 1 (LMP1) oncogene of Epstein-Barr virus can simultaneously induce and inhibit apoptosis in B cells. J Virol. 2012;86:4380-93 pubmed publisher |
| Chen Y, Chen C, Hu H, Hsueh Y. CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex. Mol Biol Cell. 2012;23:4383-92 pubmed publisher |
| Duong C, Westwood J, Yong C, Murphy A, Devaud C, John L, et al. Engineering T cell function using chimeric antigen receptors identified using a DNA library approach. PLoS ONE. 2013;8:e63037 pubmed publisher |
| Tamura H, Kawata M, Hamaguchi S, Ishikawa Y, Shiosaka S. Processing of neuregulin-1 by neuropsin regulates GABAergic neuron to control neural plasticity of the mouse hippocampus. J Neurosci. 2012;32:12657-72 pubmed publisher |
| Huet S, Fanget I, Jouannot O, Meireles P, Zeiske T, Larochette N, et al. Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane. J Neurosci. 2012;32:2564-77 pubmed publisher |
| Eisenach P, de Sampaio P, Murphy G, Roghi C. Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen. J Biol Chem. 2012;287:11533-45 pubmed publisher |
| Scheib J, Sullivan C, Carter B. Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk. J Neurosci. 2012;32:13022-31 pubmed |
| Manser C, Vagnoni A, Guillot F, Davies J, Miller C. Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity. J Neurochem. 2012;121:343-8 pubmed publisher |
| Sarkar D, Edwards S, Mauser J, Suarez A, Serowoky M, Hudok N, et al. Increased redox-sensitive green fluorescent protein reduction potential in the endoplasmic reticulum following glutathione-mediated dimerization. Biochemistry. 2013;52:3332-45 pubmed publisher |
| Kanter J, Tang C, Oram J, Bornfeldt K. Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages. Biochim Biophys Acta. 2012;1821:358-64 pubmed publisher |
| Hirata R, Nihei C, Nakano A. Isoform-selective oligomer formation of Saccharomyces cerevisiae p24 family proteins. J Biol Chem. 2013;288:37057-70 pubmed publisher |
| Panjwani N, Mulvihill E, Longuet C, Yusta B, Campbell J, Brown T, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013;154:127-39 pubmed publisher |
| Jeyaraj S, Unger N, Eid A, Mitra S, Paul El-Dahdah N, Quilliam L, et al. Cyclic AMP-Rap1A signaling activates RhoA to induce α(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. Am J Physiol Cell Physiol. 2012;303:C499-511 pubmed publisher |
| Emami-Nemini A, Gohla A, Urlaub H, Lohse M, Klenk C. The guanine nucleotide exchange factor Vav2 is a negative regulator of parathyroid hormone receptor/Gq signaling. Mol Pharmacol. 2012;82:217-25 pubmed publisher |
| Vajjhala P, Mirams R, Hill J. Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. J Biol Chem. 2012;287:41732-43 pubmed publisher |
| Walker K, Kang E, Whalen M, Shen Y, Tesco G. Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1. J Neurosci. 2012;32:10423-37 pubmed publisher |
| Dastidar S, Bardai F, Ma C, Price V, Rawat V, Verma P, et al. Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. J Neurosci. 2012;32:2846-55 pubmed publisher |
| Smith V, Sharma N, Watkins R, Read M, Ryan G, Kwan P, et al. Manipulation of PBF/PTTG1IP phosphorylation status; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors. J Clin Endocrinol Metab. 2013;98:2876-86 pubmed publisher |
| Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, et al. S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis. Cancer Res. 2013;73:172-83 pubmed publisher |
| Hughes C, Sinha U, Pandey A, Eble J, O'Callaghan C, Watson S. Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2). J Biol Chem. 2013;288:5127-35 pubmed publisher |
| Moon K, Zhang X, Zhou Q, Geahlen R. The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2. Biochim Biophys Acta. 2012;1823:199-205 pubmed publisher |
| Smith V, Read M, Turnell A, Sharma N, Lewy G, Fong J, et al. PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8. Endocrinology. 2012;153:3526-36 pubmed publisher |
| Kim J, Huh J, Hwang M, Kwon E, Jung D, Brinkmann M, et al. Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling. J Immunol. 2013;190:5287-95 pubmed publisher |
| Mórotz G, De Vos K, Vagnoni A, Ackerley S, Shaw C, Miller C. Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria. Hum Mol Genet. 2012;21:1979-88 pubmed publisher |
| Tanida I, Yamasaki M, Komatsu M, Ueno T. The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation. Autophagy. 2012;8:88-97 pubmed publisher |
| Zheng Y, Gierut J, Wang Z, Miao J, Asara J, Tyner A. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. Oncogene. 2013;32:4304-12 pubmed publisher |
| Gutekunst C, Stewart E, Franz C, English A, Gross R. PlexinA4 distribution in the adult rat spinal cord and dorsal root ganglia. J Chem Neuroanat. 2012;44:1-13 pubmed publisher |
| Manser C, Guillot F, Vagnoni A, Davies J, Lau K, McLoughlin D, et al. Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo. Oncogene. 2012;31:2773-82 pubmed publisher |
| Takasugi N, Sasaki T, Ebinuma I, Osawa S, Isshiki H, Takeo K, et al. FTY720/fingolimod, a sphingosine analogue, reduces amyloid-β production in neurons. PLoS ONE. 2013;8:e64050 pubmed publisher |
| Kim M, Ju J, Jang K, Oh S, Song J, Kim C, et al. Protein kinase Cδ negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro. Biochim Biophys Acta. 2012;1823:387-97 pubmed publisher |
| Zheng Y, Asara J, Tyner A. Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate. J Biol Chem. 2012;287:148-58 pubmed publisher |
| Schäfer A, Schubert S, Gratchev A, Seebode C, Apel A, Laspe P, et al. Characterization of three XPG-defective patients identifies three missense mutations that impair repair and transcription. J Invest Dermatol. 2013;133:1841-9 pubmed publisher |
| Li X, Lu Y, Liang K, Hsu J, Albarracin C, Mills G, et al. Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR. Oncogene. 2012;31:4372-83 pubmed publisher |
| Pfreimer M, Vatter P, Langer T, Wieland T, Gierschik P, Moepps B. LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways. Cell Signal. 2012;24:652-63 pubmed publisher |
| Sun J, Sun Q, Brown M, Dudgeon C, Chandler J, Xu X, et al. The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. PLoS ONE. 2012;7:e43158 pubmed publisher |
| Zheng Y, Wang Z, Bie W, Brauer P, Perez White B, Li J, et al. PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer. Cancer Res. 2013;73:5426-37 pubmed publisher |
