| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:1000; fig 2c
| Chung K, Hsu C, Fan L, Huang Z, Bhatia D, Chen Y, et al. Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nat Commun. 2019;10:3390 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4n
| Huang X, Yan Y, Zheng W, Ma Y, Wang X, Gong W, et al. Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction. Front Cardiovasc Med. 2021;8:682409 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5c
- western blot; human; 1:500; loading ...; fig 6f
| Xu L, Humphries F, Delagic N, Wang B, Holland A, Edgar K, et al. ECSIT is a critical limiting factor for cardiac function. JCI Insight. 2021;6: pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig s1b
| Hsiao Y, Shimizu I, Wakasugi T, Yoshida Y, Ikegami R, Hayashi Y, et al. Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. Sci Rep. 2021;11:6722 pubmed publisher |
- western blot; mouse; loading ...; fig 6c
| Chiu C, Weng Y, Huang Y, Chen R, Liu Y, Yeh T, et al. (D620N) VPS35 causes the impairment of Wnt/β-catenin signaling cascade and mitochondrial dysfunction in a PARK17 knockin mouse model. Cell Death Dis. 2020;11:1018 pubmed publisher |
- western blot; human; fig 5a
| Okur M, Fang E, Fivenson E, Tiwari V, Croteau D, Bohr V. Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling. Aging Cell. 2020;19:e13268 pubmed publisher |
- western blot; mouse; loading ...; fig 6d
| Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher |
- western blot; mouse; loading ...; fig 7s1a
| Varuzhanyan G, Rojansky R, Sweredoski M, Graham R, Hess S, Ladinsky M, et al. Mitochondrial fusion is required for spermatogonial differentiation and meiosis. elife. 2019;8: pubmed publisher |
- western blot; mouse; loading ...; fig 4b
| Oka S, Chin A, Park J, Ikeda S, Mizushima W, Ralda G, et al. Thioredoxin-1 maintains mitochondrial function via mTOR signaling in the heart. Cardiovasc Res. 2019;: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Zhao Y, Tian J, Sui S, Yuan X, Chen H, Qu C, et al. Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Sci Rep. 2017;7:7169 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3d
| Caino M, Seo J, Aguinaldo A, Wait E, Bryant K, Kossenkov A, et al. A neuronal network of mitochondrial dynamics regulates metastasis. Nat Commun. 2016;7:13730 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Barreto R, Mandili G, Witzmann F, Novelli F, Zimmers T, Bonetto A. Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways. Front Physiol. 2016;7:472 pubmed |
- western blot; mouse; fig 4
| El Sikhry H, Alsaleh N, Dakarapu R, Falck J, Seubert J. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. PLoS ONE. 2016;11:e0160380 pubmed publisher |
- immunoprecipitation; human; loading ...; fig 2e
- western blot; human; loading ...; fig 2e
| Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed publisher |
- immunocytochemistry; mouse; fig 2
- western blot; mouse; fig 4
| Luchsinger L, de Almeida M, Corrigan D, Mumau M, Snoeck H. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential. Nature. 2016;529:528-31 pubmed publisher |
| Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPK?2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed publisher |
| Yu M, Nguyen N, Huang Y, Lin D, Fujimoto T, Molkentine J, et al. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. JCI Insight. 2019;5: pubmed publisher |
| Reyes Fermín L, Avila Rojas S, Aparicio Trejo O, Tapia E, Rivero I, Pedraza Chaverri J. The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation. Antioxidants (Basel). 2019;8: pubmed publisher |
| Tang M, Vranas M, Krahn A, Pundlik S, Trempe J, Fon E. Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat Commun. 2017;8:14697 pubmed publisher |
| Lu L, Guo L, Gauba E, Tian J, Wang L, Tandon N, et al. Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice. PLoS ONE. 2015;10:e0144068 pubmed publisher |
| Chen H, Ren S, Clish C, Jain M, Mootha V, McCaffery J, et al. Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy. J Cell Biol. 2015;211:795-805 pubmed publisher |
