product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FoxO4 Antibody
catalog :
9472
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 1
Kim Muller J, Zhao S, Srivastava S, Mugabo Y, Noh H, Kim Y, et al. Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice. Cell Metab. 2014;20:593-602 pubmed publisher
  • western blot; human; 1:500
Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed publisher
  • western blot; mouse; 1:1000; fig 3a
Yang P, Li X, Xu C, Eckert R, Reece E, Zielke H, et al. Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects. Sci Signal. 2013;6:ra74 pubmed publisher
Huang P, Zhou Z, Shi F, Shao G, Wang R, Wang J, et al. Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress. Mol Med Rep. 2016;14:5116-5124 pubmed publisher
Bartell S, Kim H, Ambrogini E, Han L, Iyer S, Serra Ucer S, et al. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun. 2014;5:3773 pubmed publisher
Saben J, Zhong Y, McKelvey S, Dajani N, Andres A, Badger T, et al. A comprehensive analysis of the human placenta transcriptome. Placenta. 2014;35:125-31 pubmed publisher
Eke I, Koch U, Hehlgans S, Sandfort V, Stanchi F, Zips D, et al. PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha. J Clin Invest. 2010;120:2516-27 pubmed publisher
product information
SKU :
9472P
Product-Name :
FoxO4 Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
65
Host :
Rabbit
Target :
Foxo4
Primary-Protein :
FOXO4
Alt-Names :
AFX,AFX1,FOXO4,Fork head domain transcription factor AFX1,Forkhead box protein O4,MGC120490,MLLT7,forkhead box O4,myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila),translocated to, 7
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.